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Claudin 11 抗体

CLDN11 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265360
发货至: 中国
  • 抗原 See all Claudin 11 (CLDN11) 抗体
    Claudin 11 (CLDN11)
    适用
    • 23
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    • 15
    • 4
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    • 2
    • 1
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    人, 小鼠, 大鼠
    宿主
    • 35
    克隆类型
    • 35
    多克隆
    标记
    • 18
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
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    This Claudin 11 antibody is un-conjugated
    应用范围
    • 29
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    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects endogenous levels of Claudin 11 protein. (region surrounding Ser198)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product CLDN11 Primary Antibody
  • 应用备注
    ELISA: 1: 1000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.3, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Claudin 11 (CLDN11)
    别名
    Claudin-11 / CLDN11 (CLDN11 产品)
    别名
    cldn11 antibody, fb97c11 antibody, wu:fb97c11 antibody, claudin-11 antibody, CLDN11 antibody, Claudin-11 antibody, DKFZp459H2322 antibody, OSP antibody, OTM antibody, Claudin11 antibody, Osp antibody, Otm antibody, claudin 11b antibody, claudin 11 antibody, cldn11b antibody, CLDN11 antibody, Cldn11 antibody
    背景
    The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteinsare known to localize to tight junctions, including the Claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Emerging evidence suggests that the Claudin family of proteins regulates transport through tight junctions via differential discrimination for solute size and charge. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions.Synonyms: OSP, OTM, Oligodendrocyte-specific protein
    分子量
    approx. 24 kDa
    基因ID
    5010
    NCBI登录号
    NP_005593
    UniProt
    O75508
    途径
    Hepatitis C
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