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Caveolin-1 抗体

This anti-Caveolin-1 antibody is a 兔 多克隆 antibody detecting Caveolin-1 in WB, IF 和 EIA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN265338
发货至: 中国

Quick Overview for Caveolin-1 抗体 (ABIN265338)

抗原

See all Caveolin-1 (CAV1) 抗体
Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

适用

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人, 大鼠, 小鼠

宿主

  • 112
  • 16
  • 6
  • 2
  • 1

克隆类型

  • 105
  • 32
多克隆

标记

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  • 1
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This Caveolin-1 antibody is un-conjugated

应用范围

  • 114
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  • 25
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  • 16
  • 16
  • 10
  • 10
  • 4
  • 1
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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 特异性

    This antibody detects endogenous levels of Caveolin-1 protein (region surrounding Val163).

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography using epitope-specific immunogen

    纯度

    > 95 % pure by SDS-PAGE
  • 应用备注

    ELISA: 1: 5000 approx. 1: 10000. WB: 1: 500approx. 1: 1000. IF: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

    别名

    Caveolin-1

    背景

    Caveolae are specialised domains of the plasma membrane that are implicated in the sequestration of a variety of lipid and protein molecules. It has been suggested that these important cellular organelles have a pivotal role in such diverse biochemical processes as lipid metabolism, growth regulation, signal transduction, and apoptosis. Caveolin interacts with and regulates heterotrimeric G proteins. Currently, there are three members of the caveolin multigene family which are known to encode 21 to 24 kDa integral membrane proteins that comprise the major structural component of the caveolar membrane in vivo. Caveolin 2 protein is abundantly expressed in fibroblasts and differentiated adipocytes, smooth and skeletal muscle, and endothelial cells. The expression of caveolin 1 is similar to that of caveolin 2 while caveolin 3 expression appears to be limited to muscle tissue types.Synonyms: CAV1

    分子量

    approx. 25 kDa

    基因ID

    857

    NCBI登录号

    NP_001744

    UniProt

    Q03135

    途径

    Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals
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