BIK 抗体
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- 抗原 See all BIK 抗体
- BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BIK antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- 特异性
- The antibody detects endogenous levels of BIK protein (region surrounding Met27).
- 交叉反应 （详细）
- Species reactivity (tested):Human.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product BIK Primary Antibody
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anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) antibody
BIK 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 1-123) antibodyBIK 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 37-136) antibodyBIK 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4G12 unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (N-Term) antibodyBIK 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (N-Term) antibodyBIK 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (pThr33) antibodyBIK 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 1-123) antibodyBIK 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 39-74) antibodyBIK 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB3381 unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (pThr33) antibodyBIK 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (N-Term) antibodyBIK 适用: 人, 小鼠 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))
- 别名
- BIK (BIK 产品)
- 别名
- BIK antibody, Biklk antibody, Blk antibody, Nbk antibody, BIP1 antibody, BP4 antibody, NBK antibody, si:dkey-31f5.6 antibody, BCL2 interacting killer antibody, BCL2-interacting killer antibody, BCL2-interacting killer (apoptosis-inducing) antibody, BIK antibody, Bik antibody, bik antibody
- 背景
- Bik/Nbk (Bcl-2-interacting killer/natural born killer) is a potent pro-apoptotic protein belonging to a group of Bcl-2 family members that includes Bad, Bid, Bim, Hrk, and Noxa, containing a BH3 domain but lacking other conserved domains, BH1 or BH2. Functionally, Bik is able to bind to and antagonize anti-apoptotic Bcl-2 family members including Bcl-2, Bcl-xL, and viral homologs E1B-19K and EBV-BHFR1. The BH3 domain of Bik is essential for its apoptotic activity and interaction with survival proteins. Phosphorylation of Bik is correlated with an increase in its pro-apoptotic activity.Synonyms: Apoptosis inducer NBK, BIP1, BP4, Bcl-2-interacting killer, NBK
- 分子量
- approx. 23 kDa
- 基因ID
- 638
- NCBI登录号
- NP_001188
- UniProt
- Q13323
- 途径
- Positive Regulation of Endopeptidase Activity
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