BIK 抗体
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北京 101111
Quick Overview for BIK 抗体 (ABIN265329)
抗原
See all BIK 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The antibody detects endogenous levels of BIK protein (region surrounding Met27).
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) antibody
BIK 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 1-123) antibodyBIK 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 39-74) antibodyBIK 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB3381 unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 37-136) antibodyBIK 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4G12 unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (pThr33) antibodyBIK 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (N-Term) antibodyBIK 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (N-Term) antibodyBIK 适用: 人, 小鼠 WB, IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (AA 37-136) antibodyBIK 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4G12 unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (pThr33) antibodyBIK 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) (pThr33) antibodyBIK 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB7170 unconjugated
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))
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别名
- BIK
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背景
- Bik/Nbk (Bcl-2-interacting killer/natural born killer) is a potent pro-apoptotic protein belonging to a group of Bcl-2 family members that includes Bad, Bid, Bim, Hrk, and Noxa, containing a BH3 domain but lacking other conserved domains, BH1 or BH2. Functionally, Bik is able to bind to and antagonize anti-apoptotic Bcl-2 family members including Bcl-2, Bcl-xL, and viral homologs E1B-19K and EBV-BHFR1. The BH3 domain of Bik is essential for its apoptotic activity and interaction with survival proteins. Phosphorylation of Bik is correlated with an increase in its pro-apoptotic activity.Synonyms: Apoptosis inducer NBK, BIP1, BP4, Bcl-2-interacting killer, NBK
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分子量
- approx. 23 kDa
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基因ID
- 638
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NCBI登录号
- NP_001188
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UniProt
- Q13323
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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