alpha Adducin 抗体
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Quick Overview for alpha Adducin 抗体 (ABIN265301)
抗原
See all alpha Adducin (ADD1) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of ADD1 protein. (region surrounding Lys720)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen
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anti-Adducin 1 (Alpha) (ADD1) (AA 388-560) antibody
ADD1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adducin 1 (Alpha) (ADD1) (pSer726) antibodyADD1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adducin 1 (Alpha) (ADD1) antibodyADD1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adducin 1 (Alpha) (ADD1) antibodyKD Validated ADD1 适用: 人 WB, IF (p), FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Adducin 1 (Alpha) (ADD1) (AA 1-193) antibodyADD1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 5D4H1 unconjugated
anti-Adducin 1 (Alpha) (ADD1) (AA 1-662) antibodyADD1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2C9 unconjugated
anti-Adducin 1 (Alpha) (ADD1) antibodyADD1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Adducin 1 (Alpha) (ADD1) (Ser726) antibodyADD1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adducin 1 (Alpha) (ADD1) (pSer726) antibodyADD1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adducin 1 (Alpha) (ADD1) (Ser713), (Ser726) antibodyADD1 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IP: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))
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别名
- alpha-Adducin (ADD1)
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背景
- Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha and beta adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha and gamma adducins are ubiquitously expressed. In contrast, beta adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca2+/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms, however, not all variants have been fully described.Synonyms: ADDA, Erythrocyte adducin subunit alpha
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分子量
- approx. 81 kDa
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基因ID
- 118
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NCBI登录号
- NP_001110
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UniProt
- P35611
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途径
- Negative Regulation of Hormone Secretion, Regulation of Actin Filament Polymerization, Regulation of Lipid Metabolism by PPARalpha, ER-Nucleus Signaling
抗原
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