SRPRB 抗体 (AA 246-265)
Quick Overview for SRPRB 抗体 (AA 246-265) (ABIN265297)
抗原
See all SRPRB 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 246-265
-
特异性
- This antibody detects SRPR beta.
-
纯化方法
- Purified
-
免疫原
- Synthetic peptide corresponding to amino acids 246-265 derived from the carboxyl terminal of the canine SRbeta subunit
-
亚型
- IgG
-
-
anti-Signal Recognition Particle Receptor, B Subunit (SRPRB) antibody
SRPRB 适用: 人 WB, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 1D9 unconjugated
anti-Signal Recognition Particle Receptor, B Subunit (SRPRB) (Middle Region) antibodySRPRB 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Cow, Saccharomyces cerevisiae, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Signal Recognition Particle Receptor, B Subunit (SRPRB) antibodySRPRB 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Signal Recognition Particle Receptor, B Subunit (SRPRB) (AA 57-271) antibodySRPRB 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal Recognition Particle Receptor, B Subunit (SRPRB) (AA 58-271) antibodySRPRB 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal Recognition Particle Receptor, B Subunit (SRPRB) antibodySRPRB 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Signal Recognition Particle Receptor, B Subunit (SRPRB) (AA 58-271) antibodySRPRB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Recognition Particle Receptor, B Subunit (SRPRB) (AA 56-269) antibodySRPRB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal Recognition Particle Receptor, B Subunit (SRPRB) (AA 246-265) antibodySRPRB 适用: 犬 WB, IHC 宿主: 绵羊 Polyclonal unconjugated
anti-Signal Recognition Particle Receptor, B Subunit (SRPRB) antibodySRPRB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot: 1 to 5 μg/mL. Immunohistochemistry. Positive control: Canine microsomal protein.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- Phosphate buffered saline with 0.08 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- -20 °C
-
储存方法
- Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
-
-
- SRPRB (Signal Recognition Particle Receptor, B Subunit (SRPRB))
-
别名
- SR-beta
-
背景
- The receptor for Signal Recognition Particle (SRP) is the site on the endoplasmic reticulum that ribosomes translating secreted and integral membrane proteins are initially targeted to. Once the ribosome-SRP complex arrives at the SRP receptor the protein being translated is transferred to the translocation complex (Sec61) in the ER membrane. The SRP receptor is composed of two subunits SRalpha and SRbeta. The SRalpha subunit is a translocation GTPase peripherally bound to the endoplasmic reticulum by its interaction with SRbeta. SRalpha also binds to the GTPase of SRP (SRP54) and these two proteins appear to function as each others GTPase activating proteins (GAPs). Hydrolysis of GTP by SRalpha and SRP54 is thought to be involved in transfer of the nascent protein to the Sec61 complex in the ER. SRalpha has an apparent molecular weight of 72 kDa. SRbeta is a Type I transmembrane protein that spans the membrane once and contains Ras type GTPase domain. The function of the GTPase in SRbeta is unknown. The membrane spanning domain is at the amino-terminus of SRbeta. The GTPase domain encompasses three quarters of the protein and is carboxyl- of the transmembrane region. SRalpha binds to the GTPase domain of SRbeta. Heterodimerization of SRalpha and SRbeta masks the carboxyl-terminal epitope of SRbeta.Synonyms: APMCF1, PSEC0230, SR beta, SRPRB, Signal recognition particle receptor subunit beta
-
基因ID
- 58477
-
NCBI登录号
- NP_067026
-
UniProt
- Q9Y5M8
-
途径
- ER-Nucleus Signaling
抗原
-
