CSAG2 抗体
This anti-CSAG2 antibody is a 兔 多克隆 antibody detecting CSAG2 in WB 和 EIA. Suitable for 人.
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Quick Overview for CSAG2 抗体 (ABIN265187)
抗原
See all CSAG2 抗体
CSAG2
(CSAG Family, Member 2 (CSAG2))
适用
人
宿主
兔
克隆类型
多克隆
标记
This CSAG2 antibody is un-conjugated
应用范围
Western Blotting (WB), Enzyme Immunoassay (EIA)
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特异性
- This antibody detects Trag 3. Weakly expressed in kidney. Expressed in various tumor cell lines including carcinomas, myeloid and lymphoid malignancies, melanomas and prostate cancer. Overexpressed in taxol-resistant breast cancer line MDA 435(TR) and the doxorubicin-resistant multiple myelanoma lines 8226/Dox(40).
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纯化方法
- Purified
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免疫原
- Synthetic peptide derived from the human Trag-3 protein
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亚型
- IgG
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anti-CSAG Family, Member 2 (CSAG2) antibody
CSAG2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CSAG Family, Member 2 (CSAG2) (AA 1-30), (N-Term) antibodyCSAG2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB26828 unconjugated
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应用备注
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Western blot: 0.5-2 μg/mLELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
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- CSAG2 (CSAG Family, Member 2 (CSAG2))
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别名
- CSAG2
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背景
- The expression of the cancer-testis antigen Taxol resistance-associated gene-3 (TRAG-3) is associated with acquired paclitaxel (Taxol) resistance, and is expressed in a variety of cancers - e.g., breast cancer, leukemia, and melanoma. Overexpressed in taxol-resistant breast cancer line MDA 435(TR) and the doxorubicin-resistant multiple myelanoma lines 8226/Dox(40) and 8226/MDR(10)V. Weakly expressed in kidney. TRAG-3 is an attractive target for immunotherapy of cancer. First identified as a novel cancer/testis antigen, TRAG-3, (Taxol Resistance Associated Gene-3) was initially discovered in a search for new genes involved in drug resistance. Early studies of TRAG-3 revealed a minimal to absent expression in normal tissues and a marked over-expression in many carcinoma cell lines including several melanoma lines. By RT-PCR evaluation of TRAG-3 two transcripts are seen in many carcinoma cell lines with products in the the 799 bp and a second alternatively spliced transcript.Synonyms: CT24.2, Cancer/testis antigen 24.2, Chondrosarcoma-associated gene 2/3 protein, TRAG-3, TRAG3, Taxol-resistant-associated gene 3 protein
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基因ID
- 389903
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NCBI登录号
- NP_001074317
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UniProt
- Q9Y5P2
抗原
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