CERK 抗体
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- 抗原 See all CERK 抗体
- CERK (Ceramide Kinase (CERK))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CERK antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody reacts to Ceramide Kinase.
- 纯化方法
- Purified
- 免疫原
- Synthetic peptide derived from human ceramide kinase protein
- Top Product
- Discover our top product CERK Primary Antibody
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anti-Ceramide Kinase (CERK) (AA 212-478) antibody
CERK 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ceramide Kinase (CERK) (C-Term) antibodyCERK 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Ceramide Kinase (CERK) antibodyCERK 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ceramide Kinase (CERK) (AA 1-201) antibodyCERK 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ceramide Kinase (CERK) (AA 50-150) antibodyCERK 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ceramide Kinase (CERK) (AA 487-516), (C-Term) antibodyCERK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB5271 unconjugated
anti-Ceramide Kinase (CERK) (AA 487-516) antibodyCERK 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ceramide Kinase (CERK) (AA 1-201) antibodyCERK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ceramide Kinase (CERK) antibodyCERK 适用: 人, 猴 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ceramide Kinase (CERK) (C-Term) antibodyCERK 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Western Blot: 1 - 10 μg/mL. Positive Control: High level expression in heart, brain, skeletal muscle, kidney and liver.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- Phosphate buffered saline with 0.08 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
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- 抗原
- CERK (Ceramide Kinase (CERK))
- 别名
- Ceramide Kinase (CERK 产品)
- 别名
- AI848610 antibody, D330016D08Rik antibody, mKIAA1646 antibody, LK4 antibody, dA59H18.2 antibody, dA59H18.3 antibody, hCERK antibody, CERK antibody, si:ch211-162i19.1 antibody, MGC81777 antibody, CG16708 antibody, DCERK antibody, Dcerk antibody, Dmel\\CG16708 antibody, dcerk antibody, ceramide kinase antibody, ceramide kinase S homeolog antibody, Ceramide kinase antibody, Cerk antibody, CERK antibody, cerk antibody, cerk.S antibody, CpipJ_CPIJ003342 antibody, LOAG_11245 antibody, LOC5579301 antibody, Bm1_50005 antibody
- 背景
- Sphingolipids, in addition to being structural components of membranes, regulate cell-cell and cell-substrate interactions, proliferation, and differentiation. Members of this diverse group of lipids have emerged as a novel class of signaling molecules that also regulate phagocytosis. The mechanisms by which sphingolipids exert these effects remain incompletely defined. More than a decade ago, it was found that ceramide can be phosphorylated to ceramide 1-phosphate (C1P). Ceramide kinase (CERK) and its phosphorylated product ceramide 1-phosphate (C1P) are central players in inflammation and cancer. The product of CERK activity, ceramide 1-phosphate (C1P), has been reported to have mitogenic effects. C1P is a direct activator of cytosolic phospholipase A2 and is involved in arachidonic acid release. CERK is a mediator of Ca2+-dependent degranulation in mast cells. In both arachidonic acid release and mast cell degranulation, the intracellular elevation of Ca2+ is a central event that acts as a regulatory mechanism of CERK activity. C1P is found in brain synaptic vesicles, and plays a role in regulating the secretion of neurotransmitters. CERK activity exists in HL-60 cells where the C1P is derived from ceramide released from sphingomyelin. The expressed kinase has specific ceramide phosphorylating activity. CERKs exist in a variety of cellular organisms, including plants, nematodes, insects, and vertebrates.Synonyms: Acylsphingosine kinase, KIAA1646, LK4, Lipid kinase 4, hCERK
- 基因ID
- 64781
- NCBI登录号
- NP_073603
- UniProt
- Q8TCT0
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