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Ceremide Kinase 抗体

The 兔 多克隆 anti-Ceremide Kinase antibody is suitable to detect Ceremide Kinase in samples from 人. It has been validated for EIA 和 WB.
产品编号 ABIN265118
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Ceremide Kinase 抗体 (ABIN265118)

抗原

Ceremide Kinase

适用

宿主

克隆类型

多克隆

应用范围

Enzyme Immunoassay (EIA), Western Blotting (WB)
  • 纯化方法

    Purified

    免疫原

    Recombinant full-length human ceramide kinase protein
  • 应用备注

    ELISA. Western Blot: 1 - 10 μg/mL. Positive Control: High level expression in heart, brain, skeletal muscle, kidney and liver.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    Phosphate buffered saline with 0.08 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
  • 抗原

    Ceremide Kinase

    背景

    Sphingolipids and their metabolic products, including ceramide, sphingosine, and sphingosine-1-phosphate (S1P),1 are important signaling molecules in many biological processes. Ceramide has been is one of the key elements regulating apoptotic responses. Ceramide has been reported as a regulator of several protein kinases and phosphatases, including ceramide-activated protein kinase, protein phosphatase, and protein kinase C. Sphingosine, a metabolite of ceramide, might also play a role in mitochondriamediated apoptosis. Sphingosine inhibits several protein kinases, including protein kinase C and Ca2 -calmodulin-dependent kinase II. S1P regulates many biological processes, including mitogenesis, differentiation, migration, and suppression of apoptosis.Synonyms: Acylsphingosine kinase, LK4, Lipid kinase 4, hCERK
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