Sphingomyelin Synthase 2 抗体
Quick Overview for Sphingomyelin Synthase 2 抗体 (ABIN265116)
抗原
See all Sphingomyelin Synthase 2 (SGMS2) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody reacts to Sphingomyelin Synthase 2.
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纯化方法
- Purified
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免疫原
- Synthetic peptide derived from the human sphingomyelin synthase 2 protein.
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亚型
- IgG
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应用备注
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ELISA. Western Blot: 5 - 10 μg/mL. Positive Control: Brain, heart, kidney, liver, muscle and stomach.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline, pH 7.4
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
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- Sphingomyelin Synthase 2 (SGMS2)
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别名
- SGMS2
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背景
- Sphingomyelin (SM) is a major component of animal plasma membranes. Its production involves the transfer of phosphocholine from phosphatidylcholine and then onto ceramide. This also yields diacylglycerol as a side product. The reaction is catalysed by SM synthase, an important enzyme in the regulation of diacylglycerol and ceramide as anti- and proapoptotic stimuli. SM synthesis occurs in the lumen of the Golgi as well as on or at the cell surface. It is uncertain which SM enzyme forms are present at these differnet cellular locations. Human, mouse and Caenorhabditis elegans genomes each contain at least two different SM synthase (SMS) genes. Human SMS1 is localised to the Golgi, SMS2 resides primarily at the plasma membrane.Synonyms: SMS2, Sphingomyelin synthase 2
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基因ID
- 166929
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NCBI登录号
- NP_001129729
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UniProt
- Q8NHU3
抗原
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