MAPKBP1 抗体
Quick Overview for MAPKBP1 抗体 (ABIN2650930)
抗原
See all MAPKBP1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide of human MAPKBP1
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1) (AA 1-100) antibody
MAPKBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1) (AA 1-1015) antibodyMAPKBP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1) (N-Term) antibodyMAPKBP1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Chimpanzee, Gibbon, Gorilla, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1) (N-Term) antibodyMAPKBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1) (N-Term) antibodyMAPKBP1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:200 - 1:500
IHC 1:50 - 1:100 -
说明
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Expressed in intestinal mucosa, where it is detected in epithelial cells, endothelial cells, smooth muscle cells and immune cells, such as lymphocytes
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20C. Avoid freeze / thaw cycles.
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- MAPKBP1 (Mitogen-Activated Protein Kinase Binding Protein 1 (MAPKBP1))
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别名
- MAPKBP1
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背景
- This gene encodes a scaffold protein that regulates the JNK (c-Jun N-terminal kinase) and NOD2 (nucleotide-binding oligomerization domain-containing protein 2) signaling pathways. The encoded protein interacts with another related JNK pathway scaffold protein, WDR62, via a conserved dimerization domain, and enhances JNK signaling. This protein may play a role in bacterial immunity by binding to the NOD2 receptor and negatively regulating downstream antibacterial and pro-inflammatory signaling. Mutations in this gene that impair cellular localization of the encoded protein cause a form of nephronophthisis, an autosomal-recessive kidney disorder, in human patients.
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分子量
- 163.818 kDa
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基因ID
- 23005
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UniProt
- O60336
抗原
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