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S1PR3 抗体 (N-Term)

The 兔 多克隆 anti-S1PR3 antibody (ABIN265059) specifically detects S1PR3 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN265059
发货至: 中国
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Quick Overview for S1PR3 抗体 (N-Term) (ABIN265059)

抗原

See all S1PR3 抗体
S1PR3 (Sphingosine-1-Phosphate Receptor 3 (S1PR3))

适用

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宿主

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克隆类型

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多克隆

标记

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This S1PR3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    特异性

    This antibody reacts to EDG-3 / S1P3 / S1PR3.

    纯化方法

    Purified

    免疫原

    Synthetic peptide derived from the N terminal of the EDG3 (S1P3) protein.
  • 应用备注

    Western Blot: 5 - 10 μg/mL, Due to low expression of EDG receptors, we recommend use ofPierce Femto Signal substrate for western blot development.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    Phosphate buffered saline with 0.08 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
  • 抗原

    S1PR3 (Sphingosine-1-Phosphate Receptor 3 (S1PR3))

    别名

    EDG-3 / S1P3

    背景

    Endothelial cell differentation gene-3 (EDG3) belongs to a family of G-protein couple receptors whose ligands are lysophospholipids. The ligand for EDG3 is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family. They have been implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. The couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG3 is expressed in cardiovascular, leukocyte-containing and other tissues.Synonyms: EDG3, Endothelial differentiation G-protein coupled receptor 3, FLJ37523, FLJ93220, LPB3, MGC71696, S1P receptor 3, S1PR3, Sphingosine 1-phosphate receptor 3

    基因ID

    1903

    NCBI登录号

    NP_005217

    UniProt

    Q99500
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