S1PR3 抗体 (N-Term)
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北京 101111
Quick Overview for S1PR3 抗体 (N-Term) (ABIN265059)
抗原
See all S1PR3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody reacts to EDG-3 / S1P3 / S1PR3.
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纯化方法
- Purified
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免疫原
- Synthetic peptide derived from the N terminal of the EDG3 (S1P3) protein.
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应用备注
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Western Blot: 5 - 10 μg/mL, Due to low expression of EDG receptors, we recommend use ofPierce Femto Signal substrate for western blot development.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
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- S1PR3 (Sphingosine-1-Phosphate Receptor 3 (S1PR3))
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别名
- EDG-3 / S1P3
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背景
- Endothelial cell differentation gene-3 (EDG3) belongs to a family of G-protein couple receptors whose ligands are lysophospholipids. The ligand for EDG3 is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family. They have been implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. The couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG3 is expressed in cardiovascular, leukocyte-containing and other tissues.Synonyms: EDG3, Endothelial differentiation G-protein coupled receptor 3, FLJ37523, FLJ93220, LPB3, MGC71696, S1P receptor 3, S1PR3, Sphingosine 1-phosphate receptor 3
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基因ID
- 1903
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NCBI登录号
- NP_005217
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UniProt
- Q99500
抗原
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