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EDG4 抗体 (N-Term)

LPAR2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265051
发货至: 中国
  • 抗原 See all EDG4 (LPAR2) 抗体
    EDG4 (LPAR2) (Lysophosphatidic Acid Receptor 2 (LPAR2))
    抗原表位
    • 16
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    • 2
    • 1
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    • 1
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    N-Term
    适用
    • 43
    • 26
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    • 1
    宿主
    • 57
    • 1
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    克隆类型
    • 59
    多克隆
    标记
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    This EDG4 antibody is un-conjugated
    应用范围
    • 26
    • 22
    • 15
    • 13
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    • 7
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    Western Blotting (WB)
    特异性
    This antibody recognizes Human EDG-4 / LPA2. Other species not tested.
    纯化方法
    Purified
    免疫原
    Antibody raised against a unique synthetic peptide derived from the N-terminal of the human EDG4 protein.
    亚型
    IgG
    Top Product
    Discover our top product LPAR2 Primary Antibody
  • 应用备注
    Western Blot: 5 - 10 μg/mL, should be visualized using a high sensitivitysecondary/substrate system (i. e. Pierce's SuperSignal West Femto Maximum SensitivitySubstrate).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS, 0.08 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
  • Iwai, Koike, Ohshima, Miyatake, Uchiyama, Saeki, Ishii: "RGS18 acts as a negative regulator of osteoclastogenesis by modulating the acid-sensing OGR1/NFAT signaling pathway." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 22, Issue 10, pp. 1612-20, (2007) (PubMed).

    Jayapal, Tay, Reghunathan, Zhi, Chow, Rauff, Melendez: "Genome-wide gene expression profiling of human mast cells stimulated by IgE or FcepsilonRI-aggregation reveals a complex network of genes involved in inflammatory responses." in: BMC genomics, Vol. 7, pp. 210, (2006) (PubMed).

    Shida, Watanabe, Aoki, Hama, Kitayama, Sonoda, Kishi, Yamaguchi, Sasaki, Sako, Konishi, Arai, Nagawa: "Aberrant expression of lysophosphatidic acid (LPA) receptors in human colorectal cancer." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 84, Issue 10, pp. 1352-62, (2004) (PubMed).

  • 抗原
    EDG4 (LPAR2) (Lysophosphatidic Acid Receptor 2 (LPAR2))
    别名
    EDG-4 / LPAR2 (LPAR2 产品)
    别名
    EDG-4 antibody, EDG4 antibody, LPA-2 antibody, LPA2 antibody, lpa2 antibody, Gpbar1 antibody, Edg4 antibody, IPA2 antibody, Pbx4 antibody, RGD1561336 antibody, zgc:101053 antibody, lysophosphatidic acid receptor 2 antibody, lysophosphatidic acid receptor 2 S homeolog antibody, G protein-coupled bile acid receptor 1 antibody, growth hormone releasing hormone receptor antibody, lysophosphatidic acid receptor 2a antibody, LPAR2 antibody, lpar2.S antibody, GPBAR1 antibody, Lpar2 antibody, GHRHR antibody, lpar2a antibody
    背景
    EDG4 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG4 is lysophospholipid. There are 6 known members of the EDG receptor family and they are implicated in mediating growthrelated effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG4 is expressed in testes, ovarian tumor and leukocyte containing tissues.Synonyms: EDG4, Ipa-2, LPAR2, Lysophosphatidic acid receptor 2, Lysophosphatidic acid receptor Edg-4, endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor 4
    基因ID
    9170
    NCBI登录号
    NP_004711
    UniProt
    Q9HBW0
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