RIT2 抗体
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北京 101111
Quick Overview for RIT2 抗体 (ABIN265015)
抗原
See all RIT2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody reacts to RIT2 (Rin).
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纯化方法
- Purified
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免疫原
- His-tagged recombinant human Rin protein
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亚型
- IgG
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anti-Ras-Like Without CAAX 2 (RIT2) (AA 1-217) antibody
RIT2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F2 unconjugated
anti-Ras-Like Without CAAX 2 (RIT2) antibodyRIT2 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 4A6 unconjugated
anti-Ras-Like Without CAAX 2 (RIT2) (AA 1-150) antibodyRIT2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ras-Like Without CAAX 2 (RIT2) antibodyRIT2 适用: 人, 大鼠, 犬, 猴 WB, IHC, FACS 宿主: 小鼠 Monoclonal 3F4 unconjugated
anti-Ras-Like Without CAAX 2 (RIT2) (AA 1-217) antibodyRIT2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ras-Like Without CAAX 2 (RIT2) antibodyRIT2 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 27G2 unconjugated
anti-Ras-Like Without CAAX 2 (RIT2) (AA 119-193) antibodyRIT2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: detects recombinant Rin protein expressed in HEK-293 cells, Shows minimalcross-reactivity with Rit protein and other Ras proteins.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
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- RIT2 (Ras-Like Without CAAX 2 (RIT2))
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别名
- RIT2
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背景
- Rit and its neuron-specific homologue, Rin, define a recently discovered subfamily of Ras-related GTPases. Rit and Rin are membrane-associated in spite of the fact that they lack a CAAX box or similar C-terminal lipidation motif. Rit and Rin display 64 % amino acid sequence identity and share a unique nine amino acid effector domain (DPTIEDAYK) that is 100 % conserved between the murine and human proteins. Although the effector domain sequences of Rit and Rin are very similar to that of Ras, Rit and Rin have been shown to interact with the known Ras-binding proteins RalGDS, Rlf and AF-6, but not the Raf kinases, RIN1 or the p110 subunit of PI3 kinase. For this reason, it has been suggested that Rit and Rin may play important roles in the regulation of signaling pathways distinct from those controlled by Ras.Synonyms: GTP-binding protein Rit2, RIN, ROC2, Ras-like protein expressed in neurons, Ras-like without CAAX protein 2
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基因ID
- 6014
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NCBI登录号
- NP_002921
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UniProt
- Q99578
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途径
- Neurotrophin Signaling Pathway
抗原
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