电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

RIT2 抗体

RIT2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265015
发货至: 中国
  • 抗原 See all RIT2 抗体
    RIT2 (Ras-Like Without CAAX 2 (RIT2))
    适用
    • 30
    • 3
    • 2
    • 1
    • 1
    宿主
    • 22
    • 8
    克隆类型
    • 24
    • 6
    多克隆
    标记
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    This RIT2 antibody is un-conjugated
    应用范围
    • 25
    • 19
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody reacts to RIT2 (Rin).
    纯化方法
    Purified
    免疫原
    His-tagged recombinant human Rin protein
    亚型
    IgG
    Top Product
    Discover our top product RIT2 Primary Antibody
  • 应用备注
    Western Blot: detects recombinant Rin protein expressed in HEK-293 cells, Shows minimalcross-reactivity with Rit protein and other Ras proteins.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline with 0.08 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
  • 抗原
    RIT2 (Ras-Like Without CAAX 2 (RIT2))
    别名
    RIT2 (RIT2 产品)
    别名
    RIBA antibody, RIN antibody, ROC2 antibody, Rin antibody, Rit1 antibody, Roc2 antibody, RIT2 antibody, Ras like without CAAX 2 antibody, Ras-like without CAAX 2 antibody, RIT2 antibody, Rit2 antibody
    背景
    Rit and its neuron-specific homologue, Rin, define a recently discovered subfamily of Ras-related GTPases. Rit and Rin are membrane-associated in spite of the fact that they lack a CAAX box or similar C-terminal lipidation motif. Rit and Rin display 64 % amino acid sequence identity and share a unique nine amino acid effector domain (DPTIEDAYK) that is 100 % conserved between the murine and human proteins. Although the effector domain sequences of Rit and Rin are very similar to that of Ras, Rit and Rin have been shown to interact with the known Ras-binding proteins RalGDS, Rlf and AF-6, but not the Raf kinases, RIN1 or the p110 subunit of PI3 kinase. For this reason, it has been suggested that Rit and Rin may play important roles in the regulation of signaling pathways distinct from those controlled by Ras.Synonyms: GTP-binding protein Rit2, RIN, ROC2, Ras-like protein expressed in neurons, Ras-like without CAAX protein 2
    基因ID
    6014
    NCBI登录号
    NP_002921
    UniProt
    Q99578
    途径
    Neurotrophin Signaling Pathway
You are here:
客服