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RIT1 抗体

RIT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN265014
发货至: 中国
  • 抗原 See all RIT1 抗体
    RIT1 (Ras-Like Without CAAX 1 (RIT1))
    适用
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    宿主
    • 46
    • 3
    克隆类型
    • 47
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    多克隆
    标记
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    This RIT1 antibody is un-conjugated
    应用范围
    • 44
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    Western Blotting (WB)
    特异性
    This antibody reacts to RIT1.
    纯化方法
    Purified
    免疫原
    His-tagged recombinant human Rit protein
    亚型
    IgG
    Top Product
    Discover our top product RIT1 Primary Antibody
  • 应用备注
    Western Blot: detects recombinant Rit protein expressed in HEK-293 cells, Shows minimalcross-reactivity with Rin protein and other Ras proteins.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline with 0.08 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
  • 抗原
    RIT1 (Ras-Like Without CAAX 1 (RIT1))
    别名
    RIT1 (RIT1 产品)
    别名
    NS8 antibody, RIBB antibody, RIT antibody, ROC1 antibody, RIT1 antibody, rit1 antibody, MGC79097 antibody, RGD1559874 antibody, si:ch211-93a2.3 antibody, Rit antibody, Ras like without CAAX 1 antibody, Ras-like without CAAX 1 L homeolog antibody, Ras-like without CAAX 1 antibody, RIT1 antibody, rit1.L antibody, Rit1 antibody, rit1 antibody
    背景
    Rit and its neuron-specific homologue, Rin, define a recently discovered subfamily of Ras-related GTPases. Rit and Rin are membrane-associated in spite of the fact that they lack a CAAX box or similar C-terminal lipidation motif. Rit and Rin display 64 % amino acid sequence identity and share a unique nine amino acid effector domain (DPTIEDAYK) that is 100 % conserved between the murine and human proteins. Although the effector domain sequences of Rit and Rin are very similar to that of Ras, Rit and Rin have been shown to interact with the known Ras-binding proteins RalGDS, Rlf and AF-6, but not the Raf kinases, RIN1 or the p110 subunit of PI3 kinase. For this reason, it has been suggested that Rit and Rin may play important roles in the regulation of signaling pathways distinct from those controlled by Ras.Synonyms: RIBB, RIT, ROC1, Ras-like protein expressed in many tissues, Ras-like without CAAX protein 1
    基因ID
    6016
    NCBI登录号
    NP_008843
    UniProt
    Q92963
    途径
    Neurotrophin Signaling Pathway
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