BCL10 抗体 (AA 5-19)
Quick Overview for BCL10 抗体 (AA 5-19) (ABIN264992)
抗原
See all BCL10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 5-19
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特异性
- This antibody reacts to BCL10.
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纯化方法
- Purified
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免疫原
- Synthetic peptide corresponding to amino acids 5 to 19 of the human BCL-10 protein.
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亚型
- IgG
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anti-B-Cell CLL/lymphoma 10 (BCL10) antibody
BCL10 适用: 人, 小鼠 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 4F8 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 122-168) antibodyBCL10 适用: 人 IHC, IF, FACS, StM 宿主: 兔 Monoclonal BL10-2988R unconjugated Recombinant Antibody
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 122-168) antibodyBCL10 适用: 人 WB, IHC, FACS, StM 宿主: 小鼠 Monoclonal BL10-411 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) antibodyBCL10 适用: 人, 犬 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 6A8 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 98-234) antibodyBCL10 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3C11F4 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 1-143) antibodyBCL10 适用: 人 WB, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1185CT13-2-1-2 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) antibodyBCL10 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 1-233) antibodyBCL10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 24-51), (N-Term) antibodyBCL10 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB24271 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) antibodyBCL10 适用: 人, 小鼠 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 4F8 unconjugated
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应用备注
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Western Blot: 1 μg/mL. Detects a 31 kDa band in Raji whole cell lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline solution containing 0.02 % sodium azide as a preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- The antibody can be shipped at ambient temperature. Store (in aliquots) at 2-8 °C.
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- BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
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别名
- Bcl-10
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背景
- Apoptosis is related to many diseases including cancer. Cell death signals are transduced by death domain (DD) and caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include ARC, RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD containing protein was recently identified by several groups and designated Bcl10, CIPER, mE10, CARMEN, CLAP (1-6). Bcl10 is a cellular homolog of the equine herpesvirus-2 E-10 gene. Overexpression of Bcl10 induces JNK, p38, and NF-kB activation (1,2,4,6). Bcl10 interacts with caspase-9 and enhances pro-caspase-9 processing (3) and induces apoptosis through caspase-9 activation (3.6). BCL10 exhibits a variety of mutations in MALT lymphomas and in B and T cell lineage lymphomas indicating that it may be commonly involved in the pathogenesis of human malignancy (1,5). BCL10 is expressed in many human and murine tissues and cell lines (2-6).Synonyms: B-cell CLL/lymphoma 10, BCL10, CARD-containing molecule enhancing NF-kappa-B, CARD-like apoptotic protein, CED-3/ICH-1 prodomain homologous E10-like regulator, CIPER, CLAP, Cellular homolog of vCARMEN, Cellular-E10, Mammalian CARD-containing adapter molecule E10, c-E10, cCARMEN, hCLAP, mE10
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基因ID
- 8915
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NCBI登录号
- NP_003912
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UniProt
- O95999
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
抗原
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