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SH3BP2 抗体

SH3BP2 适用: 小鼠 WB 宿主: 绵羊 Polyclonal unconjugated
产品编号 ABIN264981
发货至: 中国
  • 抗原 See all SH3BP2 抗体
    SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
    适用
    • 40
    • 14
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 36
    • 4
    • 2
    绵羊
    克隆类型
    • 40
    • 2
    多克隆
    标记
    • 23
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SH3BP2 antibody is un-conjugated
    应用范围
    • 29
    • 20
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody reacts to 3BP2.
    纯化方法
    Purified
    免疫原
    Antibody developed using SH2 domain of the 3BP2 protein fused to GST.
    亚型
    IgG
    Top Product
    Discover our top product SH3BP2 Primary Antibody
  • 应用备注
    Western Blot: Detects a 85 kDa band in murine fibroblasts transfected with 3BP2.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline and 0.08 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
  • 抗原
    SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
    别名
    SH3BP2 (SH3BP2 产品)
    别名
    SH3BP2 antibody, 3BP-2 antibody, 3BP2 antibody, CRBM antibody, CRPM antibody, SH3 domain binding protein 2 antibody, SH3-domain binding protein 2 antibody, SH3BP2 antibody, Sh3bp2 antibody
    背景
    3BP2 (SH3 binding protein 2) was identified as a protein binding to the SH3 domain of the Abl proto-oncogene. Murine 3BP2 cDNA encodes a 559 amino acid protein of 85 kDa consisting of an N-terminal PH domain, a C-terminal SH2 domain and intervening proline-rich sequences. 3BP2 interacts via its Sh2 domain with Syk family protein tyrosine kinases Syk, Zap70, Grb2, Cbl, PLCg 1 and LAT in T lymphocytes and contributes to the transcriptional activation of NF-AT and AP-1. Mouse 3BP2 is 66 % homologous to the human protein at the amino acid level.Synonyms: 3BP-2, 3BP2, SH3 domain-binding protein 2, SH3BP-2
    基因ID
    6452
    NCBI登录号
    NP_001116153
    UniProt
    P78314
    途径
    TCR Signaling
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