DAB1 抗体 (C-Term)
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Quick Overview for DAB1 抗体 (C-Term) (ABIN264970)
抗原
See all DAB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to DAB1 (Disabled 1) (C Terminal).
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纯化方法
- Purified
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免疫原
- Recombinant protein corresponding to amino acids 399 - 555 of mouse disabled coupled to a GST fusion protein.
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亚型
- IgG
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应用备注
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Western Blot: 1 μg/mL. Immunoprecipitation: 5 μg/mL. POSITIVE CONTROL: 293 cells transfected with Dab-1-HA tag.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
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- DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))
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别名
- DAB1
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背景
- Disruption of the disabled-1 gene (Dab1) results in aberrant migration of neurons during development and disorganization of laminar structures throughout the brain. Dab1 is thought to function as an adaptor molecule in signal transduction processes. It contains a protein-protein interaction (PI) similar to the phosphotyrosine binding domain of the Shc oncoprotein, it is phosphorylated by the Src protein tyrosine kinase, and it binds to SH2 binding domains in a phosphotyrosine dependent manner. Disabled-1 acts downstream of reelin in a signalling pathway.Synonyms: Disabled homolog 1
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基因ID
- 13131
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NCBI登录号
- NP_034144
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UniProt
- P97318
抗原
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