EPH Receptor B1 抗体
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- 抗原 See all EPH Receptor B1 (EPHB1) 抗体
- EPH Receptor B1 (EPHB1)
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适用
- 人
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宿主
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绵羊
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克隆类型
- 多克隆
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标记
- This EPH Receptor B1 antibody is un-conjugated
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应用范围
- Immunoprecipitation (IP)
- 特异性
- This antibody reacts to ephB1 (Elk receptor) - EXT.
- 纯化方法
- Purified
- 亚型
- IgG
- Top Product
- Discover our top product EPHB1 Primary Antibody
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- 应用备注
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Western Blot: 1 - 10 μg/mL. Immunoprecipitation: 10 - 20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- Phosphate buffered saline with 0.08 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
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- 抗原
- EPH Receptor B1 (EPHB1)
- 别名
- EPHB1 (EPHB1 产品)
- 背景
- The immunogen used for the anti-human ephB1 (Elk receptor) -EXT region was a GST fusion protein ephB1 (Elk receptor) -EXT corresponding to amino acid sequence 16-351 of the N terminus region and having a molecular weight of 116 kD. ephB1, previously known as Elk(eph-like kinase), is a receptor tyrosine kinase of the highly tissue restricted family of eph proteins. EphB1 and other ephB family members are type 1 membrane spanning proteins, comprised of immunoglobulin, fibronectin type III, and cysteine rich subdomains in the ecto domain, and the single uninterrupted cytoplasmic tyrosine kinase domain upstream of a carboxyterminal sterile alpha motif (SAM) domain. ephB family proteins bind ephrins of the B class, ligands that are also transmembrane spanning proteins capable of transmitting signals. ephB1 is expressed predominantly in developing neural structures in embryos, and in vascular epithelium of kidney, and other tissues. Upon binding to alternatively oligomerized ephrin B1, ephB1 signals regulation of cell attachment and cellcell assembly. Members of this protein family are implicated in neuronal and vascular cell targeting.Synonyms: ELK, EPH2, EPHT2, Ephrin type-B receptor 1, HEK6, NET, Tyrosine-protein kinase receptor EPH-2
- 基因ID
- 2047
- NCBI登录号
- NP_004432
- UniProt
- P54762
- 途径
- RTK signaling
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