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EBV 抗体

EBV 适用: Epstein-Barr Virus (EBV) WB 宿主: 绵羊 Polyclonal unconjugated
产品编号 ABIN264912
发货至: 中国
  • 抗原 See all EBV products
    EBV (Epstein-Barr Virus (EBV))
    适用
    • 18
    • 6
    Epstein-Barr Virus (EBV)
    宿主
    • 15
    • 4
    • 2
    • 2
    • 1
    绵羊
    克隆类型
    • 19
    • 4
    多克隆
    标记
    • 22
    • 2
    This EBV antibody is un-conjugated
    应用范围
    • 16
    • 12
    • 9
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    Purified
    亚型
    IgG
  • 应用备注
    Western Blot: 0.25-1.00 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS, 0.08 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
  • Anderton, Yee, Smith, Crook, White, Allday: "Two Epstein-Barr virus (EBV) oncoproteins cooperate to repress expression of the proapoptotic tumour-suppressor Bim: clues to the pathogenesis of Burkitt's lymphoma." in: Oncogene, Vol. 27, Issue 4, pp. 421-33, (2008) (PubMed).

    Jiménez-Ramírez, Brooks, Forshell, Yakimchuk, Zhao, Fulgham, Sample: "Epstein-Barr virus EBNA-3C is targeted to and regulates expression from the bidirectional LMP-1/2B promoter." in: Journal of virology, Vol. 80, Issue 22, pp. 11200-8, (2006) (PubMed).

    Yuan, Cahir-McFarland, Zhao, Kieff: "Virus and cell RNAs expressed during Epstein-Barr virus replication." in: Journal of virology, Vol. 80, Issue 5, pp. 2548-65, (2006) (PubMed).

    Hong, Gulley, Feng, Delecluse, Holley-Guthrie, Kenney: "Epstein-Barr virus lytic infection contributes to lymphoproliferative disease in a SCID mouse model." in: Journal of virology, Vol. 79, Issue 22, pp. 13993-4003, (2005) (PubMed).

    Maruo, Johannsen, Illanes, Cooper, Kieff: "Epstein-Barr Virus nuclear protein EBNA3A is critical for maintaining lymphoblastoid cell line growth." in: Journal of virology, Vol. 77, Issue 19, pp. 10437-47, (2003) (PubMed).

    Rosendorff, Illanes, David, Lin, Kieff, Johannsen: "EBNA3C coactivation with EBNA2 requires a SUMO homology domain." in: Journal of virology, Vol. 78, Issue 1, pp. 367-77, (2003) (PubMed).

    ONions, Allday: "Epstein-Barr virus can inhibit genotoxin-induced G1 arrest downstream of p53 by preventing the inactivation of CDK2." in: Oncogene, Vol. 22, Issue 46, pp. 7181-91, (2003) (PubMed).

  • 抗原
    EBV (Epstein-Barr Virus (EBV))
    别名
    Epstein Barr Virus / EBV (EBV 产品)
    物质类
    Virus
    背景
    EBNA-3A is a latent viral nuclear protein expressed in EBV transformed lymphoblastic cell lines. It is also found in some immunoblastic lymphomas in vivo. This viral nuclear protein is essential for EBV mediated transformation of B lymphocytes. The EBNA-3A functions as a transcriptional regulator though the target genes are currently unknown. Plays an essential role for activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop.Synonyms: HHV-4, HHV4
    分子量
    102.4 kDa
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