Methylated Lysine (methylated) 抗体 (HRP)
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Quick Overview for Methylated Lysine (methylated) 抗体 (HRP) (ABIN264882)
抗原
宿主
克隆类型
标记
应用范围
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抗原表位
- methylated
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纯化方法
- Affinity Chromatography
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免疫原
- Methylated KLH
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亚型
- IgG
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anti-Methylated Lysine (methylated) antibody
适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Methylated Lysine (pan) antibodyWB, IHC 宿主: 小鼠 Monoclonal Mix unconjugated
anti-Methylated Lysine (pan) antibodyWB, ELISA, IHC 宿主: 小鼠 Monoclonal unconjugated
anti-Methylated Lysine antibodyWB, IHC, IF 宿主: 小鼠 Monoclonal unconjugated
anti-Methylated Lysine (pan) antibodyWB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot (4). ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.091 % Sodium Azide, 50 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing. Centrifuge vial before opening.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C up to one week or (in aliquots) at -20 °C for longer.
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- Methylated Lysine
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物质类
- Chemical
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背景
- Post-translational modifications of proteins play critical roles in the regulation and function of many known biological processes. Proteins can be post-translationally modified in many different ways, and a common posttranscriptional modification of Lysine involves methylation (1). Lysine can be methylated once, twice or three times by lysine methyltransferases. The transfer of methyl groups from S-adenosyl methionine to histones is catalyzed by enzymes known as histone methyltransferases. Histones which are methylated on certain residues can act epigenetically to repress or activate gene expression (1, 2). The transcriptional repressor SUV39H1 can encode novel enzymes which selectively methylate histone H3 at lysine 9. SUV39H1 places a methyl marker on histone H3, which is then recognized by HP1 through its chromo domain. This model may also explain the stable inheritance of the heterochromatic state (3). Some studies have also speculated a stimulatory role for transcription by methylated histone lyside 4 due to its presence at active transcription sites (4-6).
抗原
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