SOD2 抗体
Quick Overview for SOD2 抗体 (ABIN264858)
抗原
See all SOD2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Detects 25 kDa protein, corresponding to the molecular mass of Mn Superoxide Dismutase (SOD) on SDS-PAGE Immunoblots.
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纯化方法
- Antigen Affinity Chromatography
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免疫原
- Rat Mn SOD
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亚型
- IgG
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anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 25-222) antibody
SOD2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 25-222) antibodySOD2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 1-222) antibodySOD2 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 8H3D2 unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 1-222) antibodySOD2 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 8H3F9 unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) antibodySOD2 适用: 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 41-78) antibodySOD2 适用: 人, 小鼠, Pig, 绵羊 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 25-222) antibodySOD2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 64-175) antibodySOD2 适用: 人 WB, IHC, ELISA, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) (AA 119-130) antibodyVerified SOD2 适用: 人, 大鼠, 小鼠, Pig WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Superoxide Dismutase 2, Mitochondrial (SOD2) antibodySOD2 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
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应用备注
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EIA (6). Immunoprecipitation (4). Immunohistochemistry on Frozen Sections (8). Western blot (6): 0.5 μg/mL was sufficient for detection of Mn SOD in 20 μg of Rat braintissue extract.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- PBS ( pH 7.0), 0.09 % Sodium Azide, 50 % Glycerol
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储存液
- Sodium azide
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注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -28 °C for longer.
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- SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))
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别名
- Superoxide Dismutase 2 / SOD2
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背景
- Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body (3). It works by catalyzing the dismutation of the superoxide radical O2- to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (2,5). In general, SODs play a major role in antioxidant defense mechanisms (4). There are two main types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge (3). The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDa and it exists only in the extracellular space(7). SOD3 can also be distinguished by its heparin-binding capacity (1).Synonyms: Superoxide dismutase Mn
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基因ID
- 6648
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NCBI登录号
- NP_000627
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UniProt
- P04179
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途径
- Sensory Perception of Sound, Transition Metal Ion Homeostasis, Negative Regulation of intrinsic apoptotic Signaling
抗原
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