TIMP1 抗体
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北京 101111
Quick Overview for TIMP1 抗体 (ABIN264509)
抗原
See all TIMP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts to Tissue Inhibitor of Matrix Metalloproteinase 1.
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产品特性
- Synonyms: TIMP-1, TIMP, Tissue inhibitor of metalloproteinases, Metalloproteinase inhibitor 1, EPA,CLGI, Erythroid-potentiating activity, Fibroblast collagenase inhibitor
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纯化方法
- Purified
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亚型
- IgG1
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应用备注
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ELISA. Immunohistochemistry on paraffin sections: 1 - 5 μg/mL. Western Blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline with 0.08 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
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The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
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别名
- TIMP1
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背景
- TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases-1, -2, -3 and -4) complex with metalloproteinases such as collagenases, gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 was found to be identical to EPA (erythroidpotentiation activity). Parathyroid hormone has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart and low levels of TIMP-4 are expressed in liver, brain, lung, thymus and spleen.Synonyms: CLGI, EPA, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, Metalloproteinase inhibitor 1, TIMP, TIMP-1, Tissue inhibitor of metalloproteinases
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基因ID
- 7076
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UniProt
- P01033
抗原
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