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TIMP1 抗体

This anti-TIMP1 antibody is a 小鼠 单克隆 antibody detecting TIMP1 in WB, EIA 和 IHC (fro). Suitable for 人 和 猴.
产品编号 ABIN264509
发货至: 中国

Quick Overview for TIMP1 抗体 (ABIN264509)

抗原

See all TIMP1 抗体
TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

适用

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人, 猴

宿主

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小鼠

克隆类型

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单克隆

标记

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This TIMP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

2A5
  • 特异性

    This antibody reacts to Tissue Inhibitor of Matrix Metalloproteinase 1.

    产品特性

    Synonyms: TIMP-1, TIMP, Tissue inhibitor of metalloproteinases, Metalloproteinase inhibitor 1, EPA,CLGI, Erythroid-potentiating activity, Fibroblast collagenase inhibitor

    纯化方法

    Purified

    亚型

    IgG1
  • 应用备注

    ELISA. Immunohistochemistry on paraffin sections: 1 - 5 μg/mL. Western Blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    Phosphate buffered saline with 0.08 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

    别名

    TIMP1

    背景

    TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases-1, -2, -3 and -4) complex with metalloproteinases such as collagenases, gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 was found to be identical to EPA (erythroidpotentiation activity). Parathyroid hormone has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart and low levels of TIMP-4 are expressed in liver, brain, lung, thymus and spleen.Synonyms: CLGI, EPA, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, Metalloproteinase inhibitor 1, TIMP, TIMP-1, Tissue inhibitor of metalloproteinases

    基因ID

    7076

    UniProt

    P01033
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