NPDC1 抗体
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北京 101111
Quick Overview for NPDC1 抗体 (ABIN264467)
抗原
See all NPDC1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody react to NPDC-1.
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产品特性
- Synonyms: NPDC-1, Neural proliferation differentiation and control protein 1
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纯化方法
- Purified
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免疫原
- Hybridoma produced by the fusion of splenocytes from mice immunized with a syntheticpeptide derived from human NPDC-1 protein and mouse myeloma cells.
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亚型
- IgG1
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应用备注
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Western Blot: 1: 1000. Positive Control: Brain tissue lysate (mouse and rat tested, human not yet tested).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- 20 mM sodium phosphate, 150 mM sodium chloride, 50 % glycerol, pH 7.5, 3 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
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The antibody can be shipped at 2-8 °C. Store (in aliquots) at -20 °C only. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- NPDC1 (Neural Proliferation, Differentiation and Control, 1 (NPDC1))
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别名
- NPDC1
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背景
- The discovery of NPDC-1 (neuronal proliferation, differentiation and control protein 1) was the result of a study of genes that were preferentially expressed in immortalized neural precursor cell lines at the onset of contact inhibition of proliferation and subsequent differentiation. It was further found that transfection of transformed cells with NPDC-1 led to increased doubling times and suppression of many characteristics of transformation. NPDC-1 is differentially expressed in brain and lung and has been shown to interact directly with the transcription factor E2F-1 as well as D-type cyclins and cdk2. NPDC-1 has been identified as a modulator of transcriptiona levents mediated by retinoic acid and the protein level and activity of NPDC-1 have been shown to be regulated by phosphorylation mediated proteasomal degradation.Synonyms: NPDC-1, Neural proliferation differentiation and control protein 1
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基因ID
- 56654
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UniProt
- Q9NQX5
抗原
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