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S1PR4 抗体 (C-Term) (FITC)

This anti-S1PR4 antibody is a 小鼠 单克隆 antibody detecting S1PR4 in WB 和 FACS. Suitable for 人.
产品编号 ABIN264452
发货至: 中国

Quick Overview for S1PR4 抗体 (C-Term) (FITC) (ABIN264452)

抗原

See all S1PR4 抗体
S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This S1PR4 antibody is conjugated to FITC

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

1
  • 抗原表位

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    C-Term

    特异性

    Recognizes EDG-6/S1P4 (C-term).

    交叉反应 (详细)

    Species reactivity (tested):Human.

    产品特性

    Synonyms: S1P receptor 4, S1PR4, EDG6, LPC1, SLP4, Sphingosine 1-phosphate receptor 4, Endothelialdifferentiation G-protein coupled receptor 6

    免疫原

    Hybridoma produced by the fusion of splenocytes from mice immunized with Uniquesynthetic peptide derived from the C-terminal of the EDG6 (S1P4) protein and mousemyeloma cells.

    亚型

    IgG1
  • 应用备注

    Western Blot. Flow Cytometry: Use 1 μg/10^6 cells. NOTE: Epitope for the antibody is the C-terminal of the EDG6 protein. The C-terminal is anintracellular region and cells need to be permeablized prior to staining with antibody.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing containing 1 % BSA as stabilizer and 0.09 % Sodium Azide as a preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
    Shelf life: One year from despatch.

    有效期

    12 months
  • 抗原

    S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))

    别名

    S1PR4 / EDG6

    背景

    EDG6 (S1P4) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG6 (S1P4) is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG6 (S1P4) is expressed in lymphoid and hematopoietic tissue and in the lungs. Recently, the designation of the EDG receptors has been modified to include the ligand for the receptor. Thus, the new designation for the EDG6 (S1P4) receptor is the sphingosine 1-phosphate receptor-4 (S1P4).Synonyms: EDG-6, Endothelial differentiation G-protein coupled receptor 6, S1P receptor Edg-6, Sphingosine 1-phosphate receptor 4, Sphingosine 1-phosphate receptor Edg-6

    基因ID

    8698

    UniProt

    O95977
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