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SMC2 抗体 (AA 523-768)

The 小鼠 单克隆 anti-SMC2 antibody is suitable to detect SMC2 in samples from 人. It has been validated for WB.
产品编号 ABIN264446
发货至: 中国
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Quick Overview for SMC2 抗体 (AA 523-768) (ABIN264446)

抗原

See all SMC2 抗体
SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This SMC2 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

E1M
  • 抗原表位

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    AA 523-768

    特异性

    Recognizes SMC2/CAPE.

    产品特性

    Synonyms: SMC protein 2, SMC-2, SMC2L1, CAP-E, Chromosome-associated protein E, XCAP-Ehomolog, Structural maintenance of chromosomes protein 2

    纯化方法

    Purified

    免疫原

    Hybridoma produced by the fusion of splenocytes from mice immunized with recombinantprotein corresponding to amino acids 523-768 of Human CAP-E and Mouse myeloma cells. Genename: SMC2

    亚型

    IgG
  • 应用备注

    Western Blot: 1-5 μg/mL. Positive Control/Tissue Expression: HeLa cells.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.08 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

    别名

    SMC2 / CAPE

    背景

    CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintenance of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behaviour of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in human cells.Synonyms: CAP-E, Chromosome-associated protein E, SMC protein 2, SMC-2, SMC2L1, Structural maintenance of chromosomes protein 2, XCAP-E homolog

    基因ID

    10592

    UniProt

    O95347
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