RIT2 抗体
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北京 101111
Quick Overview for RIT2 抗体 (ABIN264413)
抗原
See all RIT2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody detects recombinant Rin protein expressed in 293 cells. Does not cross-react with Rit protein.
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产品特性
- Synonyms: RIN, ROC2, GTP-binding protein Rit2, Ras-like protein expressed in neurons, Ras-likewithout CAAX protein 2
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纯化方法
- Purified
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免疫原
- Hybridoma produced by the fusion of splenocytes from mice immunized with full-lengthrecombinant human Rin protein and mouse myeloma cells. Genename: RIT2
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亚型
- IgG2b
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anti-Ras-Like Without CAAX 2 (RIT2) (AA 1-217) antibody
RIT2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F2 unconjugated
anti-Ras-Like Without CAAX 2 (RIT2) antibodyRIT2 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 4A6 unconjugated
anti-Ras-Like Without CAAX 2 (RIT2) (AA 1-150) antibodyRIT2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ras-Like Without CAAX 2 (RIT2) antibodyRIT2 适用: 人, 大鼠, 犬, 猴 WB, IHC, FACS 宿主: 小鼠 Monoclonal 3F4 unconjugated
anti-Ras-Like Without CAAX 2 (RIT2) (AA 1-217) antibodyRIT2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ras-Like Without CAAX 2 (RIT2) antibodyRIT2 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 27G2 unconjugated
anti-Ras-Like Without CAAX 2 (RIT2) (AA 119-193) antibodyRIT2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot (0.5-1 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- 20 mM Sodium Phosphate, 150 mM Sodium Chloride, 50 % Glycerol at pH 7.5 and 3 mM Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
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Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch. -
有效期
- 12 months
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- RIT2 (Ras-Like Without CAAX 2 (RIT2))
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别名
- RIT2
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背景
- Rit and its neuron-specific homologue Rin, define a recently discovered subfamily of Ras-related GTPases. Rit and Rin are membrane-associated in spite of the fact that they lack a CAAX box or similar C-terminal lipidation motif. Rit and Rin display 64 % amino acid sequence identity and share a unique nine amino acid effector domain (DPTIEDAYK) that is 100 % conserved between the murine and human proteins. Although the effector domain sequences of Rit and Rin are very similar to that of Ras, Rit and Rin have been shown to interact with the known Ras-binding proteins RalGDS, Rlf and AF-6, but not the Raf kinases, RIN1 or the p110 subunit of PI3 kinase. For this reason, it has been suggested that Rit and Rin may play important roles in the regulation of signaling pathways distinct from those controlled by Ras.Synonyms: GTP-binding protein Rit2, RIN, ROC2, Ras-like protein expressed in neurons, Ras-like without CAAX protein 2
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基因ID
- 6014
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UniProt
- Q99578
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途径
- Neurotrophin Signaling Pathway
抗原
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