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RIT1 抗体

RIT1 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 14G7 unconjugated
产品编号 ABIN264412
发货至: 中国
  • 抗原 See all RIT1 抗体
    RIT1 (Ras-Like Without CAAX 1 (RIT1))
    适用
    • 36
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    • 1
    人, 小鼠
    宿主
    • 46
    • 2
    小鼠
    克隆类型
    • 47
    • 1
    单克隆
    标记
    • 20
    • 5
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    • 1
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    This RIT1 antibody is un-conjugated
    应用范围
    • 43
    • 24
    • 13
    • 13
    • 4
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    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody detects recombinant Rit protein expressed in 293 cells. Does not cross-react with Rin protein.
    产品特性
    Synonyms: RIBB, RIT, ROC1, Ras-like protein expressed in many tissues, Ras-like without CAAX protein1
    纯化方法
    Purified
    免疫原
    Hybridoma produced by the fusion of splenocytes from mice immunized with recombinantfull-length human Rit protein and mouse myeloma cells. Genename: RIT1
    克隆位点
    14G7
    亚型
    IgG1
    Top Product
    Discover our top product RIT1 Primary Antibody
  • 应用备注
    Western Blot (0.5-1 μg/mL).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    20 mM Sodium phosphate, 150 mM Sodium Chloride, 50 % Glycerol at pH 7.5 and 3 mM Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: One year from despatch.
    有效期
    12 months
  • 抗原
    RIT1 (Ras-Like Without CAAX 1 (RIT1))
    别名
    RIT1 (RIT1 产品)
    别名
    NS8 antibody, RIBB antibody, RIT antibody, ROC1 antibody, RIT1 antibody, rit1 antibody, MGC79097 antibody, RGD1559874 antibody, si:ch211-93a2.3 antibody, Rit antibody, Ras like without CAAX 1 antibody, Ras-like without CAAX 1 L homeolog antibody, Ras-like without CAAX 1 antibody, RIT1 antibody, rit1.L antibody, Rit1 antibody, rit1 antibody
    背景
    Rit and its neuron-specific homologue, Rin, define a recently discovered subfamily of Ras-related GTPases. Rit and Rin are membrane-associated in spite of the fact that they lack a CAAX box or similar C-terminal lipidation motif. Rit and Rin display 64 % amino acid sequence identity and share a unique nine amino acid effector domain (DPTIEDAYK) that is 100 % conserved between the murine and human proteins. Although the effector domain sequences of Rit and Rin are very similar to that of Ras, Rit and Rin have been shown to interact with the known Ras-binding proteins RalGDS, Rlf and AF-6, but not the Raf kinases, RIN1 or the p110 subunit of PI3 kinase. For this reason, it has been suggested that Rit and Rin may play important roles in the regulation of signaling pathways distinct from those controlled by Ras.Synonyms: RIBB, RIT, ROC1, Ras-like protein expressed in many tissues, Ras-like without CAAX protein 1
    基因ID
    6016
    UniProt
    Q92963
    途径
    Neurotrophin Signaling Pathway
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