Valproic Acid 抗体
The 小鼠 单克隆 anti-Valproic Acid antibody (Clone 801) (ABIN5610817) specifically detects Valproic Acid in EIA.
产品编号 ABIN5610817
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Valproic Acid 抗体 (ABIN5610817)
抗原
Valproic Acid
宿主
小鼠
克隆类型
单克隆
标记
This Valproic Acid antibody is un-conjugated
应用范围
Enzyme Immunoassay (EIA)
克隆位点
801
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纯化方法
- Protein G chromatography
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免疫原
- Valproic acid conjugated to KLH
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亚型
- IgG1
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应用备注
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May be used in immunoassays to detect and quantitate valproic acid.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.2mg/mL (OD280nm)
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缓冲液
- PBS, pH 7.4
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储存条件
- -20 °C
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储存方法
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Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- Valproic Acid
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物质类
- Chemical
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背景
- Valproic acid, valproate sodium and divalproex belong to the group of medicines called anticonvulsants, used to control certain types of seizures in the treatment of epilepsy. Also, valproic acid relieves histone deacetylases (HDACs) dependent transcriptional repression and causes hyperacetylation of histones in cultured cells and in vivo. Valproic acid inhibits HDAC activity in vitro, most probably by binding to the catalytic centre of HDACs. Most importantly, valproic acid induces differentiation of carcinoma cells, transformed haematopoietic progenitor cells and leukaemic blasts from acute myeloid leukaemia patients. Moreover, tumour growth and metastasis formation are significantly reduced in animal experiments. Therefore, valproic acid might serve as an effective drug for cancer therapy.
抗原
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