SNCA 抗体
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北京 101111
Quick Overview for SNCA 抗体 (ABIN264097)
抗原
See all SNCA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognizes alpha-Synuclein.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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产品特性
- Synonyms: NACP, PARK1, Non-A beta component of AD amyloid, Non-A4 component of amyloidprecursor
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纯化方法
- Protein A Chromatography.
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免疫原
- Purified E. coli produced Human alpha-synuclein
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亚型
- IgG1
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应用备注
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ELISA. Western/Dot Blot: 1/100-1/10,000. Immunohistochemistry on Frozen and Formalin-Fixed Paraffin Embedded Tissues: 1/100-1/1,000 (No formic acid, enzyme or HIER required).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- PBS without preservatives.
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储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
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Store the antibody (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- SNCA (Synuclein, alpha (SNCA))
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别名
- alpha-Synuclein / SNCA
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背景
- Synuclein-alpha is the major component of Lewy bodies and Lewy neuritis in sporadic PD. dementia with Lewy Bodies and Lewy Body variant of AD. Lewy bodies are composed of truncated and phosphorylated intermediate neurofilament proteins, alpha synuclein, ubiquitin and associated enzymes. The synuclein phosphoproteins (15-20 kDa) are small highly conserved proteins in vertebrates. The synuclein family includes alpha and beta synucleins and loosely related gamma-synuclein and synoretin. The expression is abundant in neurons and typically localized at presynaptic terminals.Synonyms: NACP, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, PARK1
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基因ID
- 6622
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UniProt
- P37840
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途径
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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