AHNAK 抗体 (N-Term)
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北京 101111
Quick Overview for AHNAK 抗体 (N-Term) (ABIN263928)
抗原
See all AHNAK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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特异性
- The antibody reacts with AHNAK1, a 700 kDa multi-functional adaptor protein expressed mainly in epithelial cell, various types of muscle cells and immune cells.
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse.
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产品特性
- Synonyms: Desmoyokin, Neuroblast differentiation-associated protein AHNAK
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纯化方法
- Protein A Affinity Chromatography
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免疫原
- Bacterially expressed fragment of N-terminal domain of human AHNAK1
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亚型
- IgG1
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anti-AHNAK Nucleoprotein (AHNAK) (N-Term) antibody
AHNAK 适用: 人, 小鼠 WB, IP, ICC, IHC (fro) 宿主: 小鼠 Monoclonal EM-09 unconjugated
anti-AHNAK Nucleoprotein (AHNAK) (AA 1-300) antibodyAHNAK 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-AHNAK Nucleoprotein (AHNAK) (AA 1-100) antibodyAHNAK 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3G7 unconjugated
anti-AHNAK Nucleoprotein (AHNAK) (AA 5689-5801) antibodyAHNAK 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-AHNAK Nucleoprotein (AHNAK) antibodyAHNAK 适用: 人 ICC, DB 宿主: 小鼠 Monoclonal 2014C3a unconjugated
anti-AHNAK Nucleoprotein (AHNAK) (AA 1-100) antibodyAHNAK 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-AHNAK Nucleoprotein (AHNAK) (C-Term) antibodyAHNAK 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-AHNAK Nucleoprotein (AHNAK) (AA 1-149) antibodyAHNAK 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-AHNAK Nucleoprotein (AHNAK) (AA 1-149) antibodyAHNAK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Immunohistochemistry on frozen sections. Western blot (Positive control: HeLa human cervix carcinoma cell line). Immunocytochemistry (Permeabilization is required, positive control: HeLa human cervixcarcinoma cell line). Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH ~7.4, 15 mM Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 to -80 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- AHNAK (AHNAK Nucleoprotein (AHNAK))
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背景
- AHNAK1 (Desmoyokin) is a large (700 kDa) scaffold protein that translocates to the plasma membrane after an increas of extracellular calcium level or upon proteinkinase C activation and regulates extracellular calcium influx mediated by L-type Ca2+ channels. AHNAK1 has been implicated in diverse signal transduction proceses affecting cell differentiation and proliferation. In response to calcium-dependent intercellular contacts AHNAK1 forms multimeric complexes in the plasma membrane, connected with actin and annexin 2/S100A10 assemblies and is thus involved in organization of the plasma membrane architecture. In epithelial cells, AHNAK1 is localized in cytoplasm or is membrane-associated, but in cells of nonepithelial origin AHNAK1 is predominantly nuclear, it has a weak DNA-binding activity and associates with the DNA-ligase IV-XRCC4 complex.Synonyms: Desmoyokin, Neuroblast differentiation-associated protein AHNAK
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基因ID
- 79026
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UniProt
- Q09666
抗原
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