CD69 抗体
(6 references)-
- 抗原 See all CD69 抗体
- CD69
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD69 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
- 特异性
- The antibody recognizes CD69, an lymphocyte early activation marker detected as a 53 kDa band under nonreducing and as 29 + 32 kDa double band under reducing SDS-PAGE conditions.
- 产品特性
- Synonyms: GP32/28, Leu-23, MLR-3, EA1, BL-AC/P26, AIM, Early T-cell activation antigen p60, Earlyactivation antigen CD69, Activation inducer molecule, C-type lectin domain family 2member C
- 纯化方法
- Affinity Chromatography on Protein A
- 免疫原
- Anti-µ-stimulated human B lymphocytes
- 克隆位点
- FN50
- 亚型
- IgG1
- Top Product
- Discover our top product CD69 Primary Antibody
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anti-CD69 (CD69) (AA 101-199) antibody
CD69 适用: 人, 小鼠 FACS, WB, ELISA, IHC (fro), IF (p), IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD69 (CD69) antibody (FITC)CD69 适用: 人 FACS 宿主: 小鼠 Monoclonal FN50 FITC
anti-CD69 (CD69) antibodyCD69 适用: 人 FACS, WB, IHC, ELISA 宿主: 小鼠 Monoclonal 8B6 unconjugated
anti-CD69 (CD69) (AA 1-199) antibodyCD69 适用: 人 FACS, WB 宿主: 小鼠 Polyclonal unconjugated
anti-CD69 (CD69) antibodyCD69 适用: 人 FACS, IHC (fro) 宿主: 小鼠 Monoclonal FN50 unconjugated
anti-CD69 (CD69) antibody (APC)CD69 适用: 人 FACS 宿主: 小鼠 Monoclonal FN50 APC
anti-CD69 (CD69) antibody (PE)CD69 适用: 人 FACS 宿主: 小鼠 Monoclonal FN50 PE
anti-CD69 (CD69) antibody (PE)CD69 适用: 人, Baboon, Cynomolgus, Macaque, 猕猴, Chimpanzee FACS 宿主: 小鼠 Monoclonal FN50 PE
anti-CD69 (CD69) (AA 62-199) antibodyCD69 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-CD69 (CD69) (AA 90-199) antibodyCD69 适用: 人 ELISA, IP 宿主: 小鼠 Monoclonal 4H3 unconjugated
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- 应用备注
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Flow Cytometry: 5 μg/mL. Western blot: 53 kDa, under reducing conditions it shows two bands of 29 and 32 kDa. Immunohistochemistry on Frozen Sections. Functional Assay: When stimulating peripheral blood T cells, FN50 antibody together withTPA synergistically increases cell volume and RNA/DNA synthesis. Addition of FN50 tostimulated peripheral blood B cells has similar, but weaker effect.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS with 15 mM Sodium Azide, pH ~7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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: "Loss of angiotensin II receptor expression in dopamine neurons in Parkinson's disease correlates with pathological progression and is accompanied by increases in Nox4- and 8-OH guanosine-related ..." in: Acta neuropathologica communications, Vol. 3, pp. 9, (2015) (PubMed).
: "Proteomic analysis reveals new cardiac-specific dystrophin-associated proteins." in: PLoS ONE, Vol. 7, Issue 8, pp. e43515, (2012) (PubMed).
: "PRR7 is a transmembrane adaptor protein expressed in activated T cells involved in regulation of T cell receptor signaling and apoptosis." in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19617-29, (2011) (PubMed).
: "Multi-parameter determination of TNF?, PCT and CRP for point-of-care testing." in: The Analyst, Vol. 136, Issue 4, pp. 692-5, (2011) (PubMed).
: "Single-molecule microscopy reveals heterogeneous dynamics of lipid raft components upon TCR engagement." in: International immunology, Vol. 19, Issue 5, pp. 675-84, (2007) (PubMed).
: "NK cell lysis of HIV-1-infected autologous CD4 primary T cells: requirement for IFN-mediated NK activation by plasmacytoid dendritic cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 4, pp. 2097-104, (2007) (PubMed).
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: "Loss of angiotensin II receptor expression in dopamine neurons in Parkinson's disease correlates with pathological progression and is accompanied by increases in Nox4- and 8-OH guanosine-related ..." in: Acta neuropathologica communications, Vol. 3, pp. 9, (2015) (PubMed).
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- 抗原
- CD69
- 别名
- CD69 (CD69 产品)
- 背景
- CD69 (C-type lectin domain family 2 C, CLEC2C, also known as AIM) is one of the earliest inducible cell surface molecules acquired during leukocyte activation. This glycoprotein serves as a lectin-type receptor in lymphocytes, NK cells and platelets, it is involved in lymphocyte proliferation. CD69 expression is counteracted on T cells in the AIDS stage of HIV infection, and may be also predictive for clinical response to chemoimmunotherapy.Synonyms: AIM, Activation inducer molecule, BL-AC/P26, C-type lectin domain family 2 member C, EA1, Early T-cell activation antigen p60, Early activation antigen CD69, GP32/28, Leu-23, MLR-3
- 基因ID
- 969
- UniProt
- Q07108
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