Bovine Coronavirus 抗体
This 小鼠 单克隆 antibody specifically detects Bovine Coronavirus in EIA. It exhibits reactivity toward Bovine Coronavirus (BCoV).
产品编号 ABIN263581
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Bovine Coronavirus 抗体 (ABIN263581)
抗原
Bovine Coronavirus (BCoV)
适用
Bovine Coronavirus (BCoV)
宿主
小鼠
克隆类型
单克隆
标记
This Bovine Coronavirus antibody is un-conjugated
应用范围
Enzyme Immunoassay (EIA)
克隆位点
5A4
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产品特性
- Synonyms: Spike glycoprotein, S glycoprotein
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纯化方法
- Protein G chromatography
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纯度
- > 95 % pure (SDS-PAGE)
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免疫原
- Bovine corona virus. Hybridization of Sp2/0 myeloma cells with spleen cells from Balb/cmice.
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亚型
- IgG1
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应用备注
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ELISA. HIT (hemagglutination inhibition titer).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.8mg/mL (OD280nm E0.1%=1.4)
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缓冲液
- PBS, pH 7.4 containing 0.09 % Sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Shelf life: one year from despatch. -
有效期
- 12 months
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- Bovine Coronavirus (BCoV)
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物质类
- Virus
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背景
- Bovine Corona Virus Spike glycoprotein is cleaved into S1 and S2 Spike proteins. The precursor is processed into S1 and S2 by host cell furin or furin-like protease to yield the mature S1 and S2 proteins. The cleavage site between S1 and S2 requires the optimal sequence [KR]-X-[KR]-R.S1 attaches the virion to the cell membrane by binding to 9-O-acetylated sialic acid containing proteins, initiating the infection.S2 is a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.Synonyms: E2 protein, Peplomer protein, S glycoprotein, Spike glycoprotein
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UniProt
- P25193
抗原
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