CTXB 抗体
This anti-CTXB antibody is a 小鼠 单克隆 antibody detecting CTXB in EIA 和 WB. Suitable for Vibrio cholerae.
Quick Overview for CTXB 抗体 (ABIN263565)
抗原
CTXB
(CtxB Gene Product (CTXB))
适用
Vibrio cholerae
宿主
小鼠
克隆类型
单克隆
标记
This CTXB antibody is un-conjugated
应用范围
Enzyme Immunoassay (EIA), Western Blotting (WB)
克隆位点
B040M
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特异性
- Reacts with cholera toxin beta subunit.
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产品特性
- Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, ctxB, toxB,VC_1456
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纯化方法
- Protein A Sepharose chromatography
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纯度
- > 90 % pure (SDS-PAGE)
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免疫原
- Purified beta subunit of cholera toxin. Hybridization of Sp2/0 myeloma cells with spleencells from Balb/c mice.
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亚型
- IgG2a
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应用备注
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ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS, pH 7.4 containing 0.09 % Sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Shelf life: one year from despatch. -
有效期
- 12 months
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- CTXB (CtxB Gene Product (CTXB))
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别名
- Cholera Enterotoxin Subunit B
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背景
- The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge. The A subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, VC_1456, ctxB, toxB
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基因ID
- 2613962
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UniProt
- P01556
抗原
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