CD13 抗体 (Biotin)
Our Local Distributor
北京 101111
Quick Overview for CD13 抗体 (Biotin) (ABIN263532)
抗原
See all CD13 (ANPEP) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- This antibody recognizes the (Mr 150-170 kDa) cell surface glycoprotein expressed in a pan-myeloid fashion. This antibody also reacts with osteoclasts in giant cell tumors of bone (osteoclastoma), clear cell chondrosarcoma and aneurysmal bone cysts.
-
交叉反应 (详细)
- Species reactivity (tested):Human.
-
产品特性
- Synonyms: Aminopeptidase N, ANPEP, APN, PEPN, Alanyl aminopeptidase, Microsomalaminopeptidase, Aminopeptidase M, gp150, Myeloid plasma membrane glycoprotein CD13
-
纯化方法
- Protein G Chromatography.
-
免疫原
- A cell suspension containing osteoclasts from osteoclastomas
-
亚型
- IgG
-
-
-
-
应用备注
-
Suitable for use in Flow Cytometry and Immunohistochemistry (acetone-fixed frozensections). We recommend using 1 μg to stain 1.0 x 10^6 cells in Flow Cytometric applications.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 0.1 mg/mL (OD280nm)
-
缓冲液
- 0.01 M PBS, pH 7.2 containing 2 mM EDTA, 1 % BSA as stabilizer and 0.09 % Sodium Azide as preservative.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
-
Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Shelf life: one year from despatch. -
有效期
- 12 months
-
-
- CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))
-
别名
- CD13
-
背景
- CD13 also known as Aminopeptidase N is a zinc dependent exopeptidase which cleaves amino acids from the N-termini of target proteins including neuropeptides and cytokines. CD13 is expressed on all cells of the myeloid lineage as well as epithelial cells of the intestine, placenta, liver and kidney. CD13 is upregulated in a number of tumour types including lung, melanoma, thyroid and hepatocarcinoma and has been shown to correlate with poor prognosis. CD13 is a crucial molecule in tumour angiogenesis. CD13 is also the receptor for viruses from the coronavirus family.Synonyms: ANPEP, APN, Alanyl aminopeptidase, Aminopeptidase M, Aminopeptidase N, Microsomal aminopeptidase, Myeloid plasma membrane glycoprotein CD13, PEPN, gp150
-
基因ID
- 290
-
UniProt
- P15144
-
途径
- Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
抗原
-