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FOXP2 抗体 (C-Term)

Cited in 5+ publications. This 山羊 多克隆 anti-FOXP2 antibody specifically detects FOXP2 in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN263146
发货至: 中国
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Quick Overview for FOXP2 抗体 (C-Term) (ABIN263146)

抗原

See all FOXP2 抗体
FOXP2 (Forkhead Box P2 (FOXP2))

适用

  • 44
  • 24
  • 14
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 34
  • 7
  • 2
  • 1
  • 1
山羊

克隆类型

  • 34
  • 10
  • 1
多克隆

标记

  • 31
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FOXP2 antibody is un-conjugated

应用范围

  • 30
  • 23
  • 13
  • 8
  • 7
  • 6
  • 5
  • 2
Western Blotting (WB), ELISA

质量等级

Verified
  • 抗原表位

    • 11
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    FOXP2 (C terminus)

    序列

    REIEEEPLSE DLE

    特异性

    This antibody is expected to recognise all three reported isoforms (NP_055306.1, NP_683696.2, NP_683697.1).

    交叉反应

    Cow, 犬, 人, 小鼠, Pig, 大鼠

    纯化方法

    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

    免疫原

    Peptide with sequence C-REIEEEPLSEDLE, from the C Terminus of the protein sequence according to NP_055306.1, NP_683696.2, NP_683697.1.

    亚型

    IgG
  • 应用备注

    Western Blot: Approx 80-90 kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 82.6 kDa according to NP_683696.2). This molecular weight is routinely observed by other sources. Recommended concentration: 0.5-2 μg/mL. Primary incubation

    Peptide ELISA: antibody detection limit dilution 1:128000.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Minimize freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Willett, Bayin, Lee, Krishnamurthy, Wojcinski, Lao, Stephen, Rosello-Diez, Dauber-Decker, Orvis, Wu, Tessier-Lavigne, Joyner: "Cerebellar nuclei excitatory neurons regulate developmental scaling of presynaptic Purkinje cell number and organ growth." in: eLife, Vol. 8, (2020) (PubMed).

    Plaas, Seppa, Reimets, Jagomäe, Toots, Koppel, Vallisoo, Nigul, Heinla, Meier, Kaasik, Piirsoo, Hickey, Terasmaa, Vasar: "Wfs1- deficient rats develop primary symptoms of Wolfram syndrome: insulin-dependent diabetes, optic nerve atrophy and medullary degeneration." in: Scientific reports, Vol. 7, Issue 1, pp. 10220, (2019) (PubMed).

    Haldipur, Dang, Aldinger, Janson, Guimiot, Adle-Biasette, Dobyns, Siebert, Russo, Millen: "Phenotypic outcomes in Mouse and Human Foxc1 dependent Dandy-Walker cerebellar malformation suggest shared mechanisms." in: eLife, Vol. 6, (2017) (PubMed).

    Fujita, Morita, Furuichi, Sugihara: "Clustered fine compartmentalization of the mouse embryonic cerebellar cortex and its rearrangement into the postnatal striped configuration." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 45, pp. 15688-703, (2012) (PubMed).

    Fujita, Sugihara: "FoxP2 expression in the cerebellum and inferior olive: development of the transverse stripe-shaped expression pattern in the mouse cerebellar cortex." in: The Journal of comparative neurology, Vol. 520, Issue 3, pp. 656-77, (2011) (PubMed).

  • 抗原

    FOXP2 (Forkhead Box P2 (FOXP2))

    别名

    FOXP2

    背景

    FOXP2, forkhead box P2, SPCH1, CAGH44, TNRC10, CAG repeat protein 44, speech and language disorder 1, trinucleotide repeat containing 10, forkhead/winged-helix transcription factor, DKFZp686H1726, OTTHUMP00000196932

    基因ID

    93986

    NCBI登录号

    NP_055306, NP_683696, NP_683697
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