MADCAM1 抗体
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北京 101111
Quick Overview for MADCAM1 抗体 (ABIN2625029)
抗原
See all MADCAM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes human mucosal addressin cell adhesion molecule 1 (MAdCAM-1), a 60kD cell surface protein that is involved in lymphocyte trafficking. MAdCAM-1 is expressed on high endothelial venules of Peyers patches and mesenteric lymph nodes. MAdCAM-1 expression has also been reported in the gut lamina propria but clone 314G8 does not recognize MAdCAM-1 in these tissues. Clone Reacts with the ligand-binding first Ig domain and reports suggest that a splice variant exists in the gut which is not recognized by clone 314G8. Clone 314G8 is reported to block the interaction of MAdCAM-1 with alpha 4 beta 7.
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纯化方法
- Protein G purified
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内毒素水平
- Low Endotoxin
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免疫原
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Recombinant soluble MAdCAM-1-fc fusion protein.
Type of Immunogen: Fusion protein -
亚型
- IgG1
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应用备注
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Approved: ELISA, Flo (1:10 - 1:100), IHC, IHC-P (10 μg/mL), WB
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunohistochemistry: This product does not require protein digestion pre-treatment of paraffin embedded sections prior to staining. This product does not require antigen retrieval prior to staining of paraffin sections. Western Blot: LS-C44686 detects a band of approximately 60kD. Reducing conditions required. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot to avoid freeze-thaw cycles. Store undiluted.
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- MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
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别名
- MADCAM1 / MAdCAM-1
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背景
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Name/Gene ID: MADCAM1
Synonyms: MADCAM1, HMAdCAM-1, MACAM1, MAdCAM-1 -
基因ID
- 8174
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UniProt
- Q13477
抗原
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