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MADCAM1 抗体

MADCAM1 适用: 人 WB, FACS, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 314G8 unconjugated
产品编号 ABIN2625029
发货至: 中国
  • 抗原 See all MADCAM1 抗体
    MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This MADCAM1 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    品牌
    IHC-plus™
    特异性
    Recognizes human mucosal addressin cell adhesion molecule 1 (MAdCAM-1), a 60kD cell surface protein that is involved in lymphocyte trafficking. MAdCAM-1 is expressed on high endothelial venules of Peyers patches and mesenteric lymph nodes. MAdCAM-1 expression has also been reported in the gut lamina propria but clone 314G8 does not recognize MAdCAM-1 in these tissues. Clone Reacts with the ligand-binding first Ig domain and reports suggest that a splice variant exists in the gut which is not recognized by clone 314G8. Clone 314G8 is reported to block the interaction of MAdCAM-1 with alpha 4 beta 7.
    纯化方法
    Protein G purified
    内毒素水平
    Low Endotoxin
    免疫原
    Recombinant soluble MAdCAM-1-fc fusion protein.

    Type of Immunogen: Fusion protein
    克隆位点
    314G8
    亚型
    IgG1
    Top Product
    Discover our top product MADCAM1 Primary Antibody
  • 应用备注
    Approved: ELISA, Flo (1:10 - 1:100), IHC, IHC-P (10 μg/mL), WB

    Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunohistochemistry: This product does not require protein digestion pre-treatment of paraffin embedded sections prior to staining. This product does not require antigen retrieval prior to staining of paraffin sections. Western Blot: LS-C44686 detects a band of approximately 60kD. Reducing conditions required. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS,  pH 7.4.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot to avoid freeze-thaw cycles. Store undiluted.
  • 抗原
    MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
    别名
    MADCAM1 / MAdCAM-1 (MADCAM1 产品)
    别名
    MACAM1 antibody, AV211525 antibody, mucosal vascular addressin cell adhesion molecule 1 antibody, MADCAM1 antibody, Madcam1 antibody
    背景
    Name/Gene ID: MADCAM1

    Synonyms: MADCAM1, HMAdCAM-1, MACAM1, MAdCAM-1
    基因ID
    8174
    UniProt
    Q13477
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