ICAM-3/CD50 抗体
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- 抗原 See all ICAM-3/CD50 (ICAM3) 抗体
- ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ICAM-3/CD50 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC)
- 特异性
- A linear epitope in domains 1 and 2 of ICAM-3. MA4 robustly inhibits apoptotic cell interaction with phagocytes.
- 纯化方法
- Purified
- 免疫原
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MA4 is a mouse monoclonal IgG1/k antibody derived by fusion of mouse Ag8.653 cells with spleen cells from a BALB/c mouse immunized with an ICAM-3/HEK transfectant.
Type of Immunogen: Cells - 克隆位点
- MA4
- 亚型
- IgG1
- Top Product
- Discover our top product ICAM3 Primary Antibody
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- 应用备注
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Approved: ELISA, Flo, ICC, IP, WB
Usage: Intercellular adhesion molecule 3 (ICAM3) also known as CD50 (Cluster of Differentiation 50), is a type I transmembrane glycoprotein, which normally contain 2-9 immunoglobulin-like C2-type domains, and binds to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. ICAM-3 has previously been implicated in apoptotic cell clearance, although its precise role in the clearance process is ill defined. - 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C, or in small aliquots at -20°C.
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- 抗原
- ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
- 别名
- ICAM3 / CD50 (ICAM3 产品)
- 背景
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Name/Gene ID: ICAM3
Family: ICAM
Synonyms: ICAM3, CD50, CDW50, ICAM-R, CD50 antigen, ICAM-3 - 基因ID
- 3385
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