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HIF3A 抗体 (AA 497-514)

This anti-HIF3A antibody is a 兔 多克隆 antibody detecting HIF3A in WB. Suitable for 人, 大鼠 和 猴.
产品编号 ABIN2621894
发货至: 中国

Quick Overview for HIF3A 抗体 (AA 497-514) (ABIN2621894)

抗原

See all HIF3A 抗体
HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

适用

人, 大鼠, 猴

宿主

  • 21
  • 4
  • 1

克隆类型

  • 25
  • 1
多克隆

标记

  • 22
  • 2
  • 1
  • 1
This HIF3A antibody is un-conjugated

应用范围

  • 20
  • 13
  • 11
  • 5
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 497-514

    特异性

    Expressed in vascular cells (at protein level) (PubMed:21069422). Expressed in kidney (PubMed:11573933, PubMed:19694616). Expressed in lung epithelial cells (PubMed:16775626). Expressed in endothelial cells (venous and arterial cells from umbilical cord and aortic endothelial cells) and in vascular smooth muscle cells (aorta) (PubMed:21069422). Strongly expressed in the heart, placenta, and skeletal muscle, whereas a weak expression profile was found in the lung, liver, and kidney (PubMed:12538644). Expressed weakly in cell renal cell carcinoma (CC-RCC) compared to normal renal cells (PubMed:16126907). Expression is down-regulated in numerous kidney tumor cells compared to non tumor kidney tissues (PubMed:16126907). Isoform 2 is expressed in heart, placenta, lung, liver, skeletal muscle and pancreas and in numerous cancer cell lines (PubMed:20416395). Isoform 3 and isoform 4 are weakly expressed in heart, placenta, lung, liver, skeletal muscle and pancreas (PubMed:20416395). Isoform 4 is expressed in fetal tissues, such as heart, brain, thymus, lung, liver, skeletal kidney and spleen (PubMed:20416395). Isoform 3 is weakly expressed in fetal tissues, such as liver and kidney (PubMed:20416395). .

    交叉反应 (详细)

    No cross reactivity with other proteins.

    纯化方法

    Immunogen affinity purified

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human HIF3(497-514aa DDDFQLNASEQLPRAYHR), different from the related rat and mouse sequences by five amino acids.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    溶解方式

    Distilled water

    浓度

    Lot specific

    缓冲液

    Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 μg antibody.

    储存液

    Sodium azide, Thimerosal (Merthiolate)

    注意事项

    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.
  • 抗原

    HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

    别名

    HIF3A / HIF3-alpha

    背景

    Name/Gene ID: HIF3A

    Synonyms: HIF3A, BHLHe17, HIF-3A, IPAS, HIF3-alpha-1, Inhibitory PAS domain protein, PASD7, HIF-3-alpha, HIF3-alpha, Member of PAS protein 7, MOP7

    基因ID

    64344

    途径

    Warburg Effect
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