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MHC Class II 抗体

This anti-MHC Class II antibody is a 大鼠 单克隆 antibody detecting MHC Class II in FACS, WB, IHC, IP, Func 和 IEM. Suitable for 小鼠.
产品编号 ABIN2568358
发货至: 中国

Quick Overview for MHC Class II 抗体 (ABIN2568358)

抗原

See all MHC Class II (MHC2) 抗体
MHC Class II (MHC2) (Major Histocompatibility Complex Class II Antigen (MHC2))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This MHC Class II antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Functional Studies (Func), Immunoelectron Microscopy (IEM)

克隆位点

M5-114-15-2
  • 特异性

    The M5/114.15.2 monoclonal antibody or (M5/114) is specific for the mouse major histocompatibility complex class II, specific for the I-A and I-E subregion-encoded glycoproteins (alloantigens I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek, but not the I-Af, I-Ak, nor I-As antigens).

    纯化方法

    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

    亚型

    IgG2b kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

    储存条件

    4 °C

    储存方法

    The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
  • 抗原

    MHC Class II (MHC2) (Major Histocompatibility Complex Class II Antigen (MHC2))

    别名

    MHC Class II

    背景

    The M5/114.15.2 monoclonal antibody or (M5/114) is specific for the mouse major histocompatibility complex class II, specific for the I-A and I-E subregion-encoded glycoproteins (alloantigens I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek, but not the I-Af, I-Ak, nor I-As antigens). The antibody also reacts with cells from the H-2p or H-2r haplotypes mice. The polymorphic determinant represented by the mouse major histocompatibility complex class II (MHC Class II) is expressed by the immune cells bearing the specified alloantigens, like T and B lymphocytes, monocytes, dendritic cells, and macrophages. The antibody doesn't react with the NOD H-2g7 haplotype alloantigens. M5/114 mAb inhibits I-A-restricted T cell responses of the Haplotypes H-2b, H-2d, H-2q, and H-2u.

    基因ID

    14961

    UniProt

    P14483
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