MER/SKY (pTyr681), (pTyr749) 抗体
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北京 101111
Quick Overview for MER/SKY (pTyr681), (pTyr749) 抗体 (ABIN2568354)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr681, pTyr749
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特异性
- The antibody detects endogenous levels of MER/SKY only when phosphorylated at tyrosine 749/681.
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纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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免疫原
- MER/SKY (phospho Tyr749/681) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 749/681 (K-I-Y (p)-S-G) derived from Human MER/SKY .
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亚型
- IgG
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应用备注
- Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store antibody at -20°C for up to one year.
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- MER/SKY
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背景
- This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
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分子量
- 97 kDa
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基因ID
- 10461, 7301
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NCBI登录号
- NP_006334
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UniProt
- Q12866, Q06418
抗原
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