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MER/SKY (pTyr681), (pTyr749) 抗体

The 兔 多克隆 anti-MER/SKY antibody is suitable to detect MER/SKY in samples from 人, 小鼠 和 大鼠. It has been validated for IHC 和 WB.
产品编号 ABIN2568354
发货至: 中国
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Quick Overview for MER/SKY (pTyr681), (pTyr749) 抗体 (ABIN2568354)

抗原

MER/SKY

适用

人, 小鼠, 大鼠

宿主

  • 9

克隆类型

  • 9
多克隆

标记

  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
非结合性

应用范围

  • 2
  • 2
  • 2
Immunohistochemistry (IHC), Western Blotting (WB)
  • 抗原表位

    • 9
    • 8
    • 1
    pTyr681, pTyr749

    特异性

    The antibody detects endogenous levels of MER/SKY only when phosphorylated at tyrosine 749/681.

    纯化方法

    Antibodies were purified by affinity-chromatography using epitope-specific peptide.

    免疫原

    MER/SKY (phospho Tyr749/681) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 749/681 (K-I-Y (p)-S-G) derived from Human MER/SKY .

    亚型

    IgG
  • 应用备注

    Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store antibody at -20°C for up to one year.
  • 抗原

    MER/SKY

    背景

    This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

    分子量

    97 kDa

    基因ID

    10461, 7301

    NCBI登录号

    NP_006334

    UniProt

    Q12866, Q06418
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