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MER/SKY (pTyr681), (pTyr749) 抗体

适用: 人, 小鼠, 大鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2568354
发货至: 中国
  • 抗原
    MER/SKY
    抗原表位
    • 9
    • 8
    • 1
    pTyr681, pTyr749
    适用
    人, 小鼠, 大鼠
    宿主
    • 9
    克隆类型
    • 9
    多克隆
    标记
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    非结合性
    应用范围
    • 2
    • 2
    • 2
    Immunohistochemistry (IHC), Western Blotting (WB)
    特异性
    The antibody detects endogenous levels of MER/SKY only when phosphorylated at tyrosine 749/681.
    纯化方法
    Antibodies were purified by affinity-chromatography using epitope-specific peptide.
    免疫原
    MER/SKY (phospho Tyr749/681) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 749/681 (K-I-Y (p)-S-G) derived from Human MER/SKY .
    亚型
    IgG
  • 应用备注
    Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store antibody at -20°C for up to one year.
  • 抗原
    MER/SKY
    背景
    This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
    分子量
    97 kDa
    基因ID
    10461, 7301
    NCBI登录号
    NP_006334
    UniProt
    Q12866, Q06418
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