ITGA4 抗体 (APC)
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Quick Overview for ITGA4 抗体 (APC) (ABIN2568299)
抗原
See all ITGA4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The DATK32 monoclonal antibody specifically reacts with an epitoPEof the Mouseα4β7 integrin (LPAM-1).
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纯化方法
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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亚型
- IgG2a kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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储存条件
- 4 °C
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储存方法
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
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- ITGA4 (Integrin alpha 4 (ITGA4))
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别名
- LPAM-1
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背景
- The DATK32 monoclonal antibody specifically reacts with an epitoPEof the Mouseα4β7 integrin (LPAM-1). The two subunits of the LPAM-1 heterodimer are the 154 kDa α4 and the 130 kDa β7. Most mature lymphocytes, a subset of bone marrow cells, and some of the thymic cells express the α4β7 integrin heterodimer. α4β7 enhances the transendothelial migration of lymphocytes, and interacts with several ligands (fibronectin, CD106, and MAdCAM-1). The interaction of DATK32 with the α4β7 induces the α4β7-dependent lymphocyte aggregation and inhibits LPAM-1-dediated cell adhesion.
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基因ID
- 16401
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UniProt
- Q00651
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途径
- Integrin Complex
抗原
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