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IZUMO1 抗体

IZUMO1 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2568277
发货至: 中国
  • 抗原 See all IZUMO1 抗体
    IZUMO1 (Izumo Sperm-Egg Fusion 1 (IZUMO1))
    适用
    • 26
    • 1
    宿主
    • 25
    • 1
    克隆类型
    • 24
    • 1
    多克隆
    标记
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    This IZUMO1 antibody is un-conjugated
    应用范围
    • 21
    • 20
    • 2
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB)
    特异性
    IZUMO1 antibody is human specific. At least four isoforms of IZUMO1 are known to exist, this antibody will detect the two longest isoforms.
    纯化方法
    IZUMO1 antibody is affinity chromatography purified via peptide column.
    免疫原
    IZUMO1 antibody was raised against an 18 amino acid peptide near the center of human IZUMO1
    亚型
    IgG
    Top Product
    Discover our top product IZUMO1 Primary Antibody
  • 应用备注
    IZUMO1 antibody can be used for detection of IZUMO1 by Western blot at 1 - 2 μ,g/mL.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    IZUMO1 antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    IZUMO1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原
    IZUMO1 (Izumo Sperm-Egg Fusion 1 (IZUMO1))
    别名
    IZUMO1 (IZUMO1 产品)
    别名
    IZUMO antibody, 1700058F15Rik antibody, Izumo antibody, izumo sperm-egg fusion 1 antibody, Ras interacting protein 1 antibody, IZUMO1 antibody, RASIP1 antibody, Izumo1 antibody
    背景
    IZUMO1, a sperm-specific protein, is essential for sperm-egg plasma membrane binding and fusion. It is involved in the fertilization process and in the fusion of the sperm with the egg (1,2). IZUMO1 is expressed as at least four isoforms produced by alternative splicing and contains one Ig-like (immunoglobulin-like) C2-type domain (3). Lack of IZUMO1 in males, due to homozygous mutation in the gene that encodes IZUMO1, results in sterility due to an inability to penetrate the plasma membrane of the egg (4).
    分子量
    Predicted: 35, 39, 42 kDa

    Observed: 52 kDa
    基因ID
    284359
    NCBI登录号
    NP_872381
    UniProt
    Q8IYV9
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