The 3G3 monoclonal antibody specifically reacts with the mouse 50-55 kDa Foxp3 protein (JM2, IPEX), a member of the forkhead family of transcription factors.
纯化方法
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
抗原
FOXP3
(Forkhead Box P3 (FOXP3))
别名
Foxp3
背景
The 3G3 monoclonal antibody specifically reacts with the mouse 50-55 kDa Foxp3 protein (JM2, IPEX), a member of the forkhead family of transcription factors. Foxp3 is expressed by the Treg lymphocytes, whose development and function are influenced by the forkhead protein. Ectopic expression of Foxp3 in T lymphocytes inhibits their activity and cytokine expression.Mutations of Foxp3 result in the "scurfy" mice phenotype.