Fc epsilon RI/FCER1A 抗体 (FITC)
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- 抗原 See all Fc epsilon RI/FCER1A (FCER1A) 抗体
- Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
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适用
- 小鼠
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宿主
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仓鼠
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克隆类型
- 单克隆
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标记
- This Fc epsilon RI/FCER1A antibody is conjugated to FITC
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The Mar-1 monoclonal antibody binds to the Fc ε Receptor I α subunit (FceR1a), which is a transmembrane glycoprotein from the immunoglobulin superfamily.
- 纯化方法
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- 克隆位点
- FceR1
- 亚型
- IgG
- Top Product
- Discover our top product FCER1A Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
- 储存条件
- 4 °C
- 储存方法
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
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- 抗原
- Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
- 别名
- Fc epsilon Receptor I alpha (FCER1A 产品)
- 背景
- The Mar-1 monoclonal antibody binds to the Fc ε Receptor I α subunit (FceR1a), which is a transmembrane glycoprotein from the immunoglobulin superfamily. FceR1a lacks signal-transducing ability and is expressed by mast and basophil cells.The Fc ε Receptor I α subunit is upregulated by IgE and forms a tetramer with a beta subunit and two gamma subunits, which have ITAM (immunoreceptor tyrosine-based activation motifs). The complex formed by the four subunits has very important roles in the IgE-facilitated allergic reactions.
- 基因ID
- 2205
- UniProt
- P12319
- 途径
- Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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