Fc epsilon RI/FCER1A 抗体
Quick Overview for Fc epsilon RI/FCER1A 抗体 (ABIN2568134)
抗原
See all Fc epsilon RI/FCER1A (FCER1A) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- The MAR-1 antibody reacts with the Fc epsilon Receptor I alpha chain (FceRIa), a transmembrane protein member of the Ig superfamily.
-
纯化方法
- The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 2 mg/mL
-
缓冲液
- Phosphate-buffered aqueous solution, ph7.2.
-
储存条件
- 4 °C
-
储存方法
- The product should be stored undiluted at 4°C. Do not freeze.
-
-
- Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
-
别名
- Fc epsilon Receptor I alpha
-
背景
- The MAR-1 antibody reacts with the Fc epsilon Receptor I alpha chain (FceRIa), a transmembrane protein member of the Ig superfamily. This chain, together with a beta chain and two gamma chains form a tetrameric complex that supports IgE-mediated signaling and subsequent release of chemical mediators of allergy and immediate hypersensitivity. FceR1a is upregulated in the presence of IgE on those cell types which express it, such as Mast cells and Basophils.The MAR-1 antibody is widely used both in flow cytometry and for depletion of cells in vitro / in vivo.
-
基因ID
- 2205
-
UniProt
- P12319
-
途径
- Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
-