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CD8 alpha 抗体 (violetFluor™ 450)

This anti-CD8 alpha antibody is a 小鼠 单克隆 antibody detecting CD8 alpha in FACS. Suitable for 人.
产品编号 ABIN2568024
发货至: 中国

Quick Overview for CD8 alpha 抗体 (violetFluor™ 450) (ABIN2568024)

抗原

See all CD8 alpha (CD8A) 抗体
CD8 alpha (CD8A) (CD8a Molecule (CD8A))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD8 alpha antibody is conjugated to violetFluor™ 450

应用范围

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Flow Cytometry (FACS)

克隆位点

RPA-T8
  • 特异性

    The RPA-T8 monoclonal antibody specifically reacts with the human CD8a molecule, a 32 kDa cell surface receptor expressed either as a heterodimer (CD8 α/β) or as a homodimer (CD8 α/α) on the majority of thymocytes, a subpopulation of mature T cells, and natural killer cells.

    纯化方法

    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

    储存条件

    4 °C

    储存方法

    The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
  • 抗原

    CD8 alpha (CD8A) (CD8a Molecule (CD8A))

    别名

    CD8a

    背景

    The RPA-T8 monoclonal antibody specifically reacts with the human CD8a molecule, a 32 kDa cell surface receptor expressed either as a heterodimer (CD8 α/β) or as a homodimer (CD8 α/α) on the majority of thymocytes, a subpopulation of mature T cells, and natural killer cells. CD8 interacts with the major histocompatibility complex class I (MHC class I) molecules on antigen-presenting cells or epithelial cells. The RPA-T8 antibody reacts with 13-48 % of peripheral lymphocytes, 80 % of thymocytes, and a subset of natural killer cells. RPA-T8, OKT8, and HIT8a antibodies do not compete with each other for binding to peripheral leukocytes, meaning that that they do not recognize the same epitope or block each other by steric hindrance.BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.

    基因ID

    925

    UniProt

    P01732

    途径

    TCR Signaling
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