CD51/CD61 抗体
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北京 101111
Quick Overview for CD51/CD61 抗体 (ABIN2567844)
抗原
See all CD51/CD61 (ITGAV/ITGB3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The 23C6 monoclonal antibody specifically reacts with the human CD51/61 Molecule, known as the integrin alpha v Beta 3 complex or vitronectin receptor.
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纯化方法
- The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
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亚型
- IgG1 kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-buffered aqueous solution, ph7.2.
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储存条件
- 4 °C
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储存方法
- The product should be stored undiluted at 4°C. Do not freeze.
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- CD51/CD61 (ITGAV/ITGB3) (Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3))
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别名
- CD51/CD61
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背景
- The 23C6 monoclonal antibody specifically reacts with the human CD51/61 Molecule, known as the integrin alpha v Beta 3 complex or vitronectin receptor. The complex binds to other ligands such as CD29, fibrinogen, fibrinectin, vWf, laminin, and thrombospondin. It is expressed by endothelial cells, osteoclasts, melanoma cells, and at low levels on platelets and macrophages. The 23C6 antibody is reported to be able to block the receptors ability to form interactions with some of its ligands.
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基因ID
- 3685, 3690
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UniProt
- P06756, P05106
抗原
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