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ITGA2 抗体

ITGA2 适用: 小鼠 FACS, Func 宿主: 仓鼠 Monoclonal HMa2 unconjugated
产品编号 ABIN2567827
发货至: 中国
  • 抗原 See all ITGA2 抗体
    ITGA2 (Integrin alpha 2 (ITGA2))
    适用
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    小鼠
    宿主
    • 67
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    仓鼠
    克隆类型
    • 85
    • 61
    单克隆
    标记
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    This ITGA2 antibody is un-conjugated
    应用范围
    • 70
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    Flow Cytometry (FACS), Functional Studies (Func)
    特异性
    The HMa2 monoclonal antibody specifically reacts with mouse CD49b (integrin alpha 2), a 150kDA transmembrane glycoprotein that forms the VLA-2 complex with CD29 (integrin beta 1).
    纯化方法
    The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
    克隆位点
    HMa2
    亚型
    IgG
    Top Product
    Discover our top product ITGA2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Phosphate-buffered aqueous solution, ph7.2.
    储存条件
    4 °C
    储存方法
    The product should be stored undiluted at 4°C. Do not freeze.
  • 抗原
    ITGA2 (Integrin alpha 2 (ITGA2))
    别名
    CD49b (ITGA2 产品)
    背景
    The HMa2 monoclonal antibody specifically reacts with mouse CD49b (integrin alpha 2), a 150kDA transmembrane glycoprotein that forms the VLA-2 complex with CD29 (integrin beta 1). VLA-2 is expressed on NK-T cells, epithelial cells, platelets, and CD+4 T lymphocytes. It is the receptor for laminin and collagen and is upregulated in response to mitogens. The Hma2 antibody is reported to partially block the interaction with collagen in T cells, but not NK cells.
    基因ID
    16398
    UniProt
    Q62469
    途径
    CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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