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CD45.2 抗体 (violetFluor™ 450)

适用: 小鼠 FACS 宿主: 小鼠 Monoclonal 104 violetFluor™ 450
产品编号 ABIN2567767
发货至: 中国
  • 抗原 See all CD45.2 products
    CD45.2 (CD45 (CD45.2 Allogen))
    适用
    小鼠
    宿主
    • 53
    小鼠
    克隆类型
    • 53
    单克隆
    标记
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD45.2 antibody is conjugated to violetFluor™ 450
    应用范围
    • 53
    • 13
    • 8
    • 3
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    特异性
    The 104 monoclonal antibody specifically reacts with the mouse CD45 Molecule, the Leukocyte Common Antigen (LCA) which occurs in the alloantigen CD45.2-expressing mouse strains (C57BL/6, CBA, 129, A, AKR, C58, DBA/1, DBA/2, BALB/c, and C3H/He).
    纯化方法
    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
    克隆位点
    104
    亚型
    IgG2a kappa
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
    储存条件
    4 °C
    储存方法
    The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
  • 抗原
    CD45.2 (CD45 (CD45.2 Allogen))
    别名
    CD45.2 (CD45.2 产品)
    背景
    The 104 monoclonal antibody specifically reacts with the mouse CD45 Molecule, the Leukocyte Common Antigen (LCA) which occurs in the alloantigen CD45.2-expressing mouse strains (C57BL/6, CBA, 129, A, AKR, C58, DBA/1, DBA/2, BALB/c, and C3H/He). The 104 monoclonal antibody does not react with the leukocytes of the CD45.1-expressing mouse strains (DA, SJL/J, RIII, and STS/A). The CD45 Molecule is a member of the Protein Tyrosine Phosphatase (PTP) family, because its intracellular region contains two PTP domains. The extracellular region's variability is caused by different levels of glycosylation, and the splicing of the 4, 5, and 6 exons. The isoforms found in the mouse strains depend on the activation state, maturation stage and cell type, and are very important in B and T lymphocytes antigen receptor signal transduction. The 104 antibody inhibits some of the B lymphocytes responses, reduces the serum IgG levels, and influences the autoimmune renal pathology. BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.
    基因ID
    19264
    UniProt
    P06800
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